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v1.0.0
ICD-10 Guide
ICD-10 CodesB44.2

B44.2

Disseminated cutaneous histoplasmosis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B44.2 is a billable code used to indicate a diagnosis of disseminated cutaneous histoplasmosis.

Key Diagnostic Point:

Disseminated cutaneous histoplasmosis is a systemic fungal infection caused by the organism Histoplasma capsulatum, which primarily affects the lungs but can disseminate to other organs, including the skin. This condition is particularly prevalent in immunocompromised individuals, such as those with HIV/AIDS, organ transplant recipients, or patients undergoing immunosuppressive therapy. Clinically, it presents with various skin lesions, which may include papules, plaques, or ulcers that can be mistaken for other dermatological conditions. Diagnosis is typically confirmed through culture, serology, or histopathological examination of skin biopsies. Treatment often involves antifungal therapy, with itraconazole being the first-line agent for mild to moderate cases, while severe cases may require amphotericin B. Early recognition and treatment are crucial to prevent further dissemination and complications, especially in vulnerable populations.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between cutaneous and disseminated forms of histoplasmosis.
  • Identifying immunocompromised status of the patient.
  • Understanding the clinical presentation and diagnostic criteria.
  • Navigating treatment options and their documentation.

Audit Risk Factors

  • Inadequate documentation of immunocompromised status.
  • Failure to document the clinical presentation of skin lesions.
  • Misclassification of the type of histoplasmosis.
  • Lack of supporting lab results or biopsy findings.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed patient history, including immunocompromised status and clinical presentation.

Common Clinical Scenarios

Patients presenting with skin lesions and a history of exposure to Histoplasma.

Billing Considerations

Ensure all lab results and treatment plans are documented clearly.

Dermatology

Documentation Requirements

Comprehensive descriptions of skin lesions and any relevant biopsy results.

Common Clinical Scenarios

Patients with atypical skin lesions that may be fungal in origin.

Billing Considerations

Differentiating between histoplasmosis and other dermatological conditions.

Coding Guidelines

Inclusion Criteria

Use B44.2 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the patient's immunocompromised status and clinical presentation
  • Include relevant lab results and treatment plans to support the diagnosis

Exclusion Criteria

Do NOT use B44.2 When
No specific exclusions found.

Related CPT Codes

88305CPT Code

Pathology examination of skin biopsy

Clinical Scenario

Used when a biopsy is performed to confirm the diagnosis of disseminated cutaneous histoplasmosis.

Documentation Requirements

Document the reason for the biopsy and the findings.

Specialty Considerations

Ensure the pathology report is included in the patient's medical record.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 allows for more specific coding of fungal infections, improving the accuracy of data collection and reimbursement processes for conditions like disseminated cutaneous histoplasmosis.

ICD-9 vs ICD-10

The transition to ICD-10 allows for more specific coding of fungal infections, improving the accuracy of data collection and reimbursement processes for conditions like disseminated cutaneous histoplasmosis.

Reimbursement & Billing Impact

reimbursement processes for conditions like disseminated cutaneous histoplasmosis.

Resources

Clinical References

  • •
    CDC - Histoplasmosis

Coding & Billing References

  • •
    CDC - Histoplasmosis

Frequently Asked Questions

What is the primary treatment for disseminated cutaneous histoplasmosis?

The primary treatment is antifungal therapy, with itraconazole being the first-line treatment for mild to moderate cases, while severe cases may require amphotericin B.