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ICD-10 Guide
ICD-10 CodesB46.2

B46.2

Pulmonary mucormycosis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B46.2 is a billable code used to indicate a diagnosis of pulmonary mucormycosis.

Key Diagnostic Point:

Pulmonary mucormycosis is a severe fungal infection caused by fungi of the Mucorales order, primarily affecting immunocompromised individuals. This condition is characterized by the invasion of the lungs by these opportunistic pathogens, leading to necrotizing pneumonia and potentially systemic dissemination. Patients often present with symptoms such as fever, cough, chest pain, and hemoptysis. The infection is particularly prevalent in individuals with underlying conditions such as diabetes mellitus, hematological malignancies, or those undergoing immunosuppressive therapy. Diagnosis typically involves imaging studies, such as CT scans, and microbiological cultures or histopathological examination of lung tissue. Prompt antifungal treatment is critical, with agents such as amphotericin B being the first line of therapy, often supplemented with surgical debridement of necrotic tissue. The prognosis is poor without timely intervention, making early recognition and treatment essential.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Requires understanding of fungal infections and their implications in immunocompromised patients.
  • Differentiation from other pulmonary infections can be challenging.
  • Documentation must clearly indicate the immunocompromised status of the patient.
  • Requires knowledge of specific antifungal treatments and their indications.

Audit Risk Factors

  • Inadequate documentation of immunocompromised status.
  • Failure to document the specific antifungal treatment administered.
  • Lack of clarity in distinguishing mucormycosis from other fungal infections.
  • Insufficient clinical details regarding the patient's presenting symptoms.

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed clinical notes on the patient's immunocompromised status, symptoms, diagnostic tests, and treatment plans.

Common Clinical Scenarios

Patients with hematological malignancies presenting with respiratory symptoms and fever.

Billing Considerations

Documentation must include the type of immunosuppression and any prior antifungal treatments.

Pulmonology

Documentation Requirements

Thorough pulmonary function tests, imaging results, and treatment response notes.

Common Clinical Scenarios

Patients with chronic lung disease who develop acute respiratory distress.

Billing Considerations

Need to document the extent of lung involvement and any surgical interventions performed.

Coding Guidelines

Inclusion Criteria

Use B46.2 When
  • Follow the official ICD
  • CM coding guidelines for infectious diseases, ensuring accurate documentation of the patient's immunocompromised status and the specific nature of the fungal infection
  • Include any relevant laboratory results and imaging studies that support the diagnosis

Exclusion Criteria

Do NOT use B46.2 When
No specific exclusions found.

Related CPT Codes

88305CPT Code

Pathology examination of lung biopsy

Clinical Scenario

Used when lung tissue is biopsied to confirm mucormycosis.

Documentation Requirements

Pathology report must indicate the presence of Mucorales.

Specialty Considerations

Infectious disease specialists should ensure that the biopsy is appropriately indicated.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of fungal infections, improving the accuracy of data collection and reimbursement processes for conditions like pulmonary mucormycosis.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of fungal infections, improving the accuracy of data collection and reimbursement processes for conditions like pulmonary mucormycosis.

Reimbursement & Billing Impact

reimbursement processes for conditions like pulmonary mucormycosis.

Resources

Clinical References

  • •
    CDC Guidelines on Fungal Infections

Coding & Billing References

  • •
    CDC Guidelines on Fungal Infections

Frequently Asked Questions

What are the common symptoms of pulmonary mucormycosis?

Common symptoms include fever, cough, chest pain, and hemoptysis, particularly in immunocompromised patients.

How is pulmonary mucormycosis diagnosed?

Diagnosis typically involves imaging studies, microbiological cultures, and histopathological examination of lung tissue.

What is the first-line treatment for pulmonary mucormycosis?

The first-line treatment is usually amphotericin B, often in conjunction with surgical debridement of affected tissue.