Central nervous system histoplasmosis
ICD-10 B47.1 is a billable code used to indicate a diagnosis of central nervous system histoplasmosis.
Central nervous system histoplasmosis is a rare but serious fungal infection caused by the organism Histoplasma capsulatum. This pathogen is typically found in soil enriched with bird or bat droppings. The infection can manifest in various forms, with the central nervous system (CNS) being a critical site of involvement. Patients may present with symptoms such as headache, fever, altered mental status, and neurological deficits. The diagnosis is often confirmed through lumbar puncture, revealing fungal elements in cerebrospinal fluid (CSF) or through serological tests. Immunocompromised individuals, such as those with HIV/AIDS, organ transplant recipients, or patients on immunosuppressive therapy, are at a significantly higher risk for developing CNS histoplasmosis. Treatment typically involves antifungal medications, with amphotericin B being the first-line therapy, followed by itraconazole for maintenance therapy. Early diagnosis and treatment are crucial to prevent severe complications, including permanent neurological damage or death.
Detailed clinical notes on symptoms, lab results, and treatment plans.
Patients presenting with fever, headache, and neurological symptoms.
Ensure documentation reflects the immunocompromised status and any prior treatments.
Neurological assessments, imaging results, and CSF analysis.
Patients with altered mental status and neurological deficits.
Document neurological findings thoroughly to support coding.
Used when fungal infection is suspected.
Document the source of the culture and clinical indications.
Infectious disease specialists should ensure cultures are obtained appropriately.
Common symptoms include severe headaches, fever, confusion, and neurological deficits. Patients may also experience seizures or altered mental status.
Diagnosis is typically made through lumbar puncture to analyze cerebrospinal fluid, along with serological tests for Histoplasma capsulatum.
Treatment usually involves antifungal therapy, starting with amphotericin B followed by itraconazole for maintenance.
