ICD-10 Logo
ICDxICD-10 Medical Coding
ICD-10 Logo
ICDxICD-10 Medical Coding
ICD 10 CodesDiagnoses
ICD 10 CodesDiagnoses
ICD-10 Logo
ICDxICD-10 Medical Coding

Comprehensive ICD-10-CM code reference with AI-powered search capabilities.

© 2025 ICD Code Compass. All rights reserved.

Browse

  • All Chapters
  • All Categories
  • Diagnoses

Tools

  • AI Code Search
ICD-10-CM codes are maintained by the CDC and CMS. This tool is for reference purposes only.
v1.0.0
ICD-10 Guide
ICD-10 CodesB57.40

B57.40

Chagas' disease with nervous system involvement, unspecified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 B57.40 is a billable code used to indicate a diagnosis of chagas' disease with nervous system involvement, unspecified.

Key Diagnostic Point:

Chagas' disease, caused by the protozoan parasite Trypanosoma cruzi, is endemic to parts of Latin America and can lead to serious health complications, including nervous system involvement. The disease is primarily transmitted through the bite of infected triatomine bugs, but can also be contracted through blood transfusions, organ transplants, and from mother to child. The acute phase may present with mild symptoms such as fever and fatigue, but the chronic phase can lead to severe complications, including cardiomyopathy and neurological disorders. When the nervous system is involved, patients may experience symptoms such as seizures, meningoencephalitis, or peripheral neuropathy. Diagnosis typically involves serological tests to detect antibodies against T. cruzi, and imaging studies may be used to assess organ involvement. Treatment primarily includes antiparasitic medications such as benznidazole or nifurtimox, which are most effective during the acute phase. Management of neurological symptoms may require additional supportive therapies. Due to the complexity of the disease and its varied presentations, accurate coding is essential for appropriate treatment and reimbursement.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Varied clinical presentations and symptoms
  • Differentiation from other tropical diseases
  • Potential for co-morbid conditions
  • Need for comprehensive documentation of neurological involvement

Audit Risk Factors

  • Inadequate documentation of neurological symptoms
  • Misclassification of the disease stage
  • Failure to document co-morbid conditions
  • Inconsistent use of diagnostic tests

Specialty Focus

Medical Specialties

Infectious Disease

Documentation Requirements

Detailed patient history, serological test results, and treatment response.

Common Clinical Scenarios

Patients presenting with acute or chronic Chagas' disease symptoms, particularly neurological manifestations.

Billing Considerations

Ensure documentation reflects the complexity of the disease and any co-existing conditions.

Neurology

Documentation Requirements

Neurological examination findings, imaging results, and treatment plans.

Common Clinical Scenarios

Patients with neurological symptoms such as seizures or neuropathy secondary to Chagas' disease.

Billing Considerations

Document the relationship between Chagas' disease and neurological symptoms clearly.

Coding Guidelines

Inclusion Criteria

Use B57.40 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the disease's stage and any neurological involvement
  • Include any relevant co
  • morbid conditions to support the diagnosis

Exclusion Criteria

Do NOT use B57.40 When
No specific exclusions found.

Related CPT Codes

86701CPT Code

Antibody test for Trypanosoma cruzi

Clinical Scenario

Used to confirm diagnosis of Chagas' disease.

Documentation Requirements

Document the reason for testing and any relevant clinical findings.

Specialty Considerations

Infectious disease specialists should ensure comprehensive documentation of test results.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of Chagas' disease and its complications, improving the accuracy of diagnosis and treatment tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of Chagas' disease and its complications, improving the accuracy of diagnosis and treatment tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of Chagas' disease and its complications, improving the accuracy of diagnosis and treatment tracking.

Resources

Clinical References

  • •
    CDC Chagas Disease Information

Coding & Billing References

  • •
    CDC Chagas Disease Information

Frequently Asked Questions

What are the common symptoms of Chagas' disease?

Common symptoms include fever, fatigue, swelling at the site of infection, and in chronic cases, cardiac and neurological complications.