B57.49

Chagas' disease, caused by the protozoan parasite Trypanosoma cruzi, is endemic to parts of Latin America and can lead to significant neurological complications. The disease progresses through acute and chronic phases, with the chronic phase often resulting in various forms of nervous system involvement. Patients may experience peripheral neuropathy, meningoencephalitis, or other central nervous system manifestations. Symptoms can include seizures, cognitive impairment, and motor dysfunction. Diagnosis typically involves serological tests for antibodies against T. cruzi, and imaging studies may be utilized to assess neurological damage. Treatment primarily focuses on antiparasitic medications such as benznidazole or nifurtimox, which are most effective during the acute phase. In chronic cases, symptomatic management and supportive care are essential, particularly for neurological symptoms. The complexity of managing Chagas' disease lies in its varied presentations and the need for multidisciplinary approaches to address both the infectious and neurological aspects of the disease.