Meningoencephalitis due to Acanthamoeba (culbertsoni)
ICD-10 B60.11 is a billable code used to indicate a diagnosis of meningoencephalitis due to acanthamoeba (culbertsoni).
Meningoencephalitis due to Acanthamoeba (culbertsoni) is a rare but serious infection of the central nervous system caused by the protozoan Acanthamoeba. This organism is commonly found in soil, fresh water, and even in the air, making it a ubiquitous environmental pathogen. The infection typically occurs in immunocompromised individuals or those with pre-existing conditions, such as chronic lung disease or diabetes. Symptoms may include fever, headache, neck stiffness, altered mental status, and focal neurological deficits. Diagnosis is often challenging and requires a combination of clinical evaluation, imaging studies, and laboratory tests, including PCR for Acanthamoeba DNA in cerebrospinal fluid (CSF). Treatment usually involves a combination of antimicrobial therapy, including anti-amoebic agents such as pentamidine and miltefosine, and supportive care. Early recognition and intervention are crucial to improving outcomes, as the disease can progress rapidly and lead to significant morbidity and mortality.
Detailed clinical notes on symptoms, laboratory results, and treatment plans.
Patients presenting with neurological symptoms and a history of exposure to contaminated water.
Ensure that all laboratory findings are documented, especially PCR results for Acanthamoeba.
Comprehensive neurological assessments and imaging results.
Patients with acute neurological decline and CSF analysis indicating infection.
Document any differential diagnoses considered and ruled out.
Used when confirming the diagnosis of Acanthamoeba meningoencephalitis.
Documentation of the clinical suspicion and rationale for testing.
Infectious disease specialists should ensure that all relevant clinical information is included.
Common symptoms include fever, headache, neck stiffness, altered mental status, and focal neurological deficits. Symptoms can progress rapidly, necessitating prompt medical attention.
