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v1.0.0
ICD-10 Guide
ICD-10 CodesC46.50

C46.50

Billable

Kaposi's sarcoma of unspecified lung

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C46.50 is a billable code used to indicate a diagnosis of kaposi's sarcoma of unspecified lung.

Key Diagnostic Point:

Kaposi's sarcoma (KS) is a vascular tumor associated with human herpesvirus 8 (HHV-8) infection, primarily affecting individuals with compromised immune systems, particularly those with HIV/AIDS. It can manifest in various forms, including classic, endemic, iatrogenic, and epidemic (associated with HIV). When KS affects the lungs, it can lead to respiratory symptoms such as cough, hemoptysis, and dyspnea. The diagnosis is often confirmed through imaging studies and biopsy. In patients with HIV, the presence of KS is indicative of advanced immunosuppression, and it may signify a poor prognosis. Treatment options for pulmonary KS include antiretroviral therapy (ART) to manage HIV, chemotherapy, and localized therapies such as radiation. The management of KS requires a multidisciplinary approach, often involving oncologists, infectious disease specialists, and palliative care teams to address both the cancer and the underlying HIV infection.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Requires understanding of HIV/AIDS and its association with KS.
  • Differentiation from other lung conditions that may present similarly.
  • Need for precise documentation of the extent and location of the disease.
  • Potential for multiple treatment modalities impacting coding.

Audit Risk Factors

  • Inadequate documentation of HIV status.
  • Failure to specify the extent of lung involvement.
  • Misclassification of KS as a primary lung cancer.
  • Inconsistent coding of treatment modalities.

Specialty Focus

Medical Specialties

Oncology

Documentation Requirements

Detailed pathology reports and imaging studies.

Common Clinical Scenarios

Patients presenting with respiratory symptoms and known HIV status.

Billing Considerations

Need for comprehensive treatment documentation, including ART and chemotherapy.

Infectious Disease

Documentation Requirements

HIV viral load and CD4 counts, treatment history.

Common Clinical Scenarios

Patients with advanced HIV presenting with opportunistic infections or malignancies.

Billing Considerations

Coordination with oncology for integrated care plans.

Coding Guidelines

Inclusion Criteria

Use C46.50 When
  • Follow ICD
  • CM guidelines for neoplasms, ensuring accurate documentation of the primary site and any associated conditions
  • Include relevant details about HIV status and treatment history

Exclusion Criteria

Do NOT use C46.50 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

96413CPT Code

Chemotherapy administration, intravenous

Clinical Scenario

Used for patients receiving chemotherapy for KS.

Documentation Requirements

Document the specific chemotherapy regimen and patient response.

Specialty Considerations

Oncology specialists must ensure accurate coding of chemotherapy sessions.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of Kaposi's sarcoma, improving the accuracy of data collection and reimbursement processes. It has also facilitated better tracking of KS in relation to HIV/AIDS.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of Kaposi's sarcoma, improving the accuracy of data collection and reimbursement processes. It has also facilitated better tracking of KS in relation to HIV/AIDS.

Reimbursement & Billing Impact

reimbursement processes. It has also facilitated better tracking of KS in relation to HIV/AIDS.

Resources

Clinical References

  • •
    Kaposi's Sarcoma Research Center

Coding & Billing References

  • •
    Kaposi's Sarcoma Research Center

Frequently Asked Questions

What is the significance of coding C46.50?

Coding C46.50 accurately reflects the diagnosis of Kaposi's sarcoma affecting the lungs, which is crucial for appropriate treatment planning and reimbursement. It also highlights the need for comprehensive management of the patient's HIV status.