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ICD-10 Guide
ICD-10 CodesC54.1

C54.1

Billable

Malignant neoplasm of endometrium

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C54.1 is a billable code used to indicate a diagnosis of malignant neoplasm of endometrium.

Key Diagnostic Point:

C54.1 refers to malignant neoplasms of the endometrium, which is the inner lining of the uterus. This condition is commonly known as endometrial cancer and is one of the most prevalent gynecologic malignancies. It typically arises from the glandular cells of the endometrium and is often associated with abnormal uterine bleeding, pelvic pain, and other symptoms. Risk factors include obesity, diabetes, hypertension, and prolonged exposure to estrogen without progesterone. Diagnosis is usually confirmed through endometrial biopsy, imaging studies, and sometimes hysteroscopy. The staging of endometrial cancer is crucial for determining treatment options and prognosis, with stages ranging from I (confined to the uterus) to IV (spread to distant organs). CA-125, a tumor marker, may be elevated in cases of endometrial cancer, although it is not specific to this malignancy. Surgical approaches often include total abdominal hysterectomy with bilateral salpingo-oophorectomy (TAH-BSO) and may be accompanied by lymphadenectomy depending on the stage of the disease.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in staging and treatment protocols
  • Need for precise documentation of symptoms and risk factors
  • Differentiation from other gynecologic malignancies
  • Potential for co-morbid conditions affecting coding

Audit Risk Factors

  • Inadequate documentation of staging
  • Failure to capture co-morbid conditions
  • Misclassification of the type of neoplasm
  • Inconsistent use of tumor markers in documentation

Specialty Focus

Medical Specialties

Gynecologic Oncology

Documentation Requirements

Detailed pathology reports, imaging studies, and surgical notes are essential for accurate coding.

Common Clinical Scenarios

Diagnosis and treatment planning for endometrial cancer, management of post-operative complications.

Billing Considerations

Ensure that all relevant staging information and treatment modalities are documented to support coding.

Radiology

Documentation Requirements

Clear imaging reports that specify findings related to endometrial cancer.

Common Clinical Scenarios

Pre-operative imaging for staging and post-operative follow-up imaging.

Billing Considerations

Radiology reports should correlate with clinical findings and treatment plans.

Coding Guidelines

Inclusion Criteria

Use C54.1 When
  • According to the official coding guidelines, C54
  • 1 should be used when the diagnosis of malignant neoplasm of the endometrium is confirmed
  • Coders must ensure that the documentation supports the diagnosis and includes staging information

Exclusion Criteria

Do NOT use C54.1 When
  • Exclusion criteria include benign conditions and other malignancies not affecting the endometrium

Related ICD-10 Codes

Related CPT Codes

58150CPT Code

Total abdominal hysterectomy

Clinical Scenario

Used in the surgical treatment of endometrial cancer.

Documentation Requirements

Operative report detailing the procedure and findings.

Specialty Considerations

Gynecologic oncology specialists should ensure comprehensive documentation of the surgical approach.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of endometrial cancer, improving the accuracy of data collection and reimbursement processes. It enables better tracking of treatment outcomes and resource utilization.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of endometrial cancer, improving the accuracy of data collection and reimbursement processes. It enables better tracking of treatment outcomes and resource utilization.

Reimbursement & Billing Impact

reimbursement processes. It enables better tracking of treatment outcomes and resource utilization.

Resources

Clinical References

  • •
    American Cancer Society - Endometrial Cancer

Coding & Billing References

  • •
    American Cancer Society - Endometrial Cancer

Frequently Asked Questions

What are the common symptoms of endometrial cancer?

Common symptoms include abnormal uterine bleeding, pelvic pain, and changes in menstrual patterns. Patients may also experience weight loss and fatigue.

How is endometrial cancer staged?

Endometrial cancer is staged based on the extent of tumor invasion, lymph node involvement, and presence of metastasis, typically classified from stage I to IV.