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v1.0.0
ICD-10 Guide
ICD-10 CodesC82.10

C82.10

Billable

Follicular lymphoma grade II, unspecified site

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C82.10 is a billable code used to indicate a diagnosis of follicular lymphoma grade ii, unspecified site.

Key Diagnostic Point:

Follicular lymphoma grade II is a type of non-Hodgkin lymphoma characterized by the proliferation of follicle center (germinal center) B-cells. It is classified as a low to intermediate-grade lymphoma, indicating a moderate growth rate. This condition typically presents with painless lymphadenopathy, and it can involve multiple lymph node regions or extranodal sites. The unspecified site designation indicates that the exact location of the lymphoma has not been determined or documented. Patients may experience B-symptoms, which include fever, night sweats, and weight loss, indicating a more aggressive disease course. Diagnosis is often confirmed through lymph node biopsy and immunophenotyping. Treatment options may include watchful waiting, chemotherapy, immunotherapy, or radiation therapy, depending on the stage of the disease and the patient's overall health. The prognosis varies, with many patients achieving long-term remission, although the disease can be relapsing in nature.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in clinical presentation and staging
  • Need for precise documentation of lymph node involvement
  • Differentiation from other types of lymphomas
  • Potential for B-symptoms to influence treatment decisions

Audit Risk Factors

  • Inadequate documentation of lymph node sites
  • Failure to document B-symptoms
  • Misclassification of lymphoma grade
  • Lack of treatment documentation

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Detailed documentation of diagnosis, staging, treatment plans, and follow-up care.

Common Clinical Scenarios

Patients presenting with lymphadenopathy, B-symptoms, or those undergoing treatment for follicular lymphoma.

Billing Considerations

Ensure accurate grading and staging are documented to support coding and treatment decisions.

Pathology

Documentation Requirements

Comprehensive reports on biopsy results, including histological grading and immunophenotyping.

Common Clinical Scenarios

Biopsy specimens from lymph nodes or extranodal sites for diagnosis confirmation.

Billing Considerations

Pathology reports must clearly indicate the grade and type of lymphoma for accurate coding.

Coding Guidelines

Inclusion Criteria

Use C82.10 When
  • Follow the ICD
  • CM coding guidelines for neoplasms, ensuring accurate documentation of the site and grade
  • Include any relevant B
  • symptoms and treatment details to support the diagnosis

Exclusion Criteria

Do NOT use C82.10 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

88305CPT Code

Pathology examination of lymph node biopsy

Clinical Scenario

Used when a biopsy is performed to confirm the diagnosis of follicular lymphoma.

Documentation Requirements

Pathology report must include the diagnosis and grade.

Specialty Considerations

Pathologists should ensure accurate grading and type identification.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of follicular lymphoma, improving the accuracy of data collection and treatment tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of follicular lymphoma, improving the accuracy of data collection and treatment tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of follicular lymphoma, improving the accuracy of data collection and treatment tracking.

Resources

Clinical References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Coding & Billing References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Frequently Asked Questions

What is the significance of the grade in follicular lymphoma?

The grade indicates the aggressiveness of the lymphoma, with higher grades typically associated with a more rapid progression and different treatment approaches.