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ICD-10 Guide
ICD-10 CodesC82.29

C82.29

Billable

Follicular lymphoma grade III, unspecified, extranodal and solid organ sites

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C82.29 is a billable code used to indicate a diagnosis of follicular lymphoma grade iii, unspecified, extranodal and solid organ sites.

Key Diagnostic Point:

Follicular lymphoma grade III is a subtype of non-Hodgkin lymphoma characterized by the proliferation of follicle center (germinal center) B-cells. This specific grade indicates a more aggressive form of the disease, often associated with a higher proliferation index and a poorer prognosis compared to lower grades. The term 'extranodal' refers to the involvement of lymphoid tissue outside of the lymph nodes, which can include organs such as the spleen, liver, or bone marrow. Patients may present with B-symptoms, which include fever, night sweats, and weight loss, indicating systemic involvement. Diagnosis typically involves a combination of imaging studies, biopsy, and histological examination to confirm the presence of neoplastic follicle center cells. Treatment protocols may include chemotherapy, immunotherapy, or targeted therapies, depending on the stage of the disease and the patient's overall health. The management of follicular lymphoma grade III often requires a multidisciplinary approach, involving oncologists, hematologists, and radiologists.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Differentiation between grades of follicular lymphoma
  • Extranodal involvement requiring detailed documentation
  • Potential for staging variations impacting treatment
  • Need for comprehensive patient history to assess B-symptoms

Audit Risk Factors

  • Inadequate documentation of B-symptoms
  • Failure to specify extranodal involvement
  • Incorrect grading of lymphoma
  • Lack of comprehensive treatment documentation

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Detailed pathology reports, imaging studies, and treatment plans.

Common Clinical Scenarios

Diagnosis and management of newly diagnosed follicular lymphoma, treatment response evaluation.

Billing Considerations

Ensure accurate staging and grading are documented to support treatment decisions.

Radiology

Documentation Requirements

Imaging reports detailing extranodal involvement and staging.

Common Clinical Scenarios

Imaging for staging and follow-up of lymphoma treatment.

Billing Considerations

Clear documentation of findings related to extranodal sites is crucial.

Coding Guidelines

Inclusion Criteria

Use C82.29 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the diagnosis, including the grade and extranodal involvement

Exclusion Criteria

Do NOT use C82.29 When
  • Exclude codes for other types of lymphomas unless specified

Related ICD-10 Codes

Related CPT Codes

96413CPT Code

Chemotherapy administration, intravenous

Clinical Scenario

Used during treatment of follicular lymphoma grade III.

Documentation Requirements

Document the specific chemotherapy regimen and patient response.

Specialty Considerations

Oncology specialists must ensure accurate coding of chemotherapy administration.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of lymphomas, including the ability to capture the grade and extranodal involvement, which is crucial for treatment planning and outcomes tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of lymphomas, including the ability to capture the grade and extranodal involvement, which is crucial for treatment planning and outcomes tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of lymphomas, including the ability to capture the grade and extranodal involvement, which is crucial for treatment planning and outcomes tracking.

Resources

Clinical References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Coding & Billing References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Frequently Asked Questions

What are the key symptoms of follicular lymphoma grade III?

Key symptoms include B-symptoms such as fever, night sweats, and unexplained weight loss, along with lymphadenopathy and possible extranodal involvement.