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v1.0.0
ICD-10 Guide
ICD-10 CodesC82.38

C82.38

Billable

Follicular lymphoma grade IIIa, lymph nodes of multiple sites

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C82.38 is a billable code used to indicate a diagnosis of follicular lymphoma grade iiia, lymph nodes of multiple sites.

Key Diagnostic Point:

Follicular lymphoma is a type of non-Hodgkin lymphoma characterized by the proliferation of follicle center (germinal center) B-cells. Grade IIIa indicates a more aggressive form of the disease, where there is a predominance of large cells, but not all cells are large. This subtype typically presents with lymphadenopathy in multiple sites, which can include cervical, axillary, and inguinal lymph nodes. Patients may exhibit B-symptoms such as fever, night sweats, and unexplained weight loss, which are indicative of systemic involvement. Diagnosis is confirmed through histopathological examination and immunophenotyping, often requiring a biopsy of affected lymph nodes. Treatment protocols may include watchful waiting for asymptomatic patients, chemotherapy regimens such as R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone), and targeted therapies. The prognosis varies based on the stage at diagnosis, patient age, and overall health, with advanced stages generally associated with a poorer outcome.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiation between grades of follicular lymphoma
  • Need for accurate staging based on lymph node involvement
  • Documentation of B-symptoms and their impact on treatment
  • Variability in treatment protocols based on patient presentation

Audit Risk Factors

  • Inadequate documentation of B-symptoms
  • Failure to specify the grade of lymphoma
  • Misinterpretation of staging criteria
  • Inconsistent treatment documentation

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Detailed clinical notes on patient history, physical examination findings, and treatment plans.

Common Clinical Scenarios

Diagnosis and management of newly diagnosed follicular lymphoma, treatment response evaluations, and management of relapsed disease.

Billing Considerations

Ensure accurate grading and staging are documented to support coding and treatment decisions.

Pathology

Documentation Requirements

Comprehensive pathology reports including histological findings and immunophenotyping results.

Common Clinical Scenarios

Biopsy evaluations for suspected lymphoma and grading of lymphoid tissues.

Billing Considerations

Pathology reports must clearly indicate the grade and subtype of lymphoma for accurate coding.

Coding Guidelines

Inclusion Criteria

Use C82.38 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the lymphoma grade and staging
  • Include any relevant B
  • symptoms and treatment plans in the medical record

Exclusion Criteria

Do NOT use C82.38 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

96413CPT Code

Chemotherapy administration, intravenous

Clinical Scenario

Used during treatment of follicular lymphoma grade IIIa.

Documentation Requirements

Document the specific chemotherapy regimen and patient response.

Specialty Considerations

Oncology specialists must ensure accurate coding of chemotherapy administration.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of lymphoma subtypes, improving the accuracy of data collection and treatment tracking.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of lymphoma subtypes, improving the accuracy of data collection and treatment tracking.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of lymphoma subtypes, improving the accuracy of data collection and treatment tracking.

Resources

Clinical References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Coding & Billing References

  • •
    National Comprehensive Cancer Network (NCCN) Guidelines

Frequently Asked Questions

What are the key symptoms of follicular lymphoma grade IIIa?

Key symptoms include lymphadenopathy, fever, night sweats, and unexplained weight loss, known as B-symptoms.