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v1.0.0
ICD-10 Guide
ICD-10 CodesC82.54

C82.54

Billable

Diffuse follicle center lymphoma, lymph nodes of axilla and upper limb

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C82.54 is a billable code used to indicate a diagnosis of diffuse follicle center lymphoma, lymph nodes of axilla and upper limb.

Key Diagnostic Point:

Diffuse follicle center lymphoma (DFCL) is a subtype of non-Hodgkin lymphoma characterized by the proliferation of neoplastic B-cells within the follicle center of lymphoid tissue. This condition primarily affects the lymph nodes, particularly in the axillary and upper limb regions. Clinically, patients may present with painless lymphadenopathy, often accompanied by systemic B-symptoms such as fever, night sweats, and weight loss. The disease can be indolent or aggressive, necessitating careful staging to determine the extent of lymph node involvement and potential dissemination to other sites. Staging is typically performed using the Ann Arbor classification, which assesses the number of lymph node regions involved and the presence of extranodal disease. Treatment protocols may include watchful waiting for indolent cases, chemotherapy regimens such as R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone), and radiation therapy for localized disease. The prognosis varies based on the stage at diagnosis and the patient's overall health.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiation from other types of lymphomas
  • Need for precise staging and documentation
  • Variability in treatment protocols based on patient factors
  • Potential for B-symptoms to influence coding

Audit Risk Factors

  • Inadequate documentation of B-symptoms
  • Failure to accurately stage the disease
  • Misidentification of lymph node locations
  • Inconsistent treatment documentation

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Detailed clinical notes on lymph node examination, staging, and treatment plans.

Common Clinical Scenarios

Patients presenting with lymphadenopathy, B-symptoms, or those undergoing chemotherapy.

Billing Considerations

Ensure accurate documentation of all treatment modalities and patient responses.

Pathology

Documentation Requirements

Histopathological reports confirming the diagnosis of diffuse follicle center lymphoma.

Common Clinical Scenarios

Biopsy specimens from lymph nodes showing follicular patterns.

Billing Considerations

Clear identification of the lymphoma subtype and grading.

Coding Guidelines

Inclusion Criteria

Use C82.54 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the diagnosis, staging, and any associated symptoms
  • Include details on lymph node involvement and treatment plans

Exclusion Criteria

Do NOT use C82.54 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

96413CPT Code

Chemotherapy administration, intravenous

Clinical Scenario

Used during treatment for diffuse follicle center lymphoma.

Documentation Requirements

Document the specific chemotherapy regimen and patient response.

Specialty Considerations

Oncology specialists must ensure accurate coding of chemotherapy sessions.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of lymphomas, improving the accuracy of data collection and treatment tracking. C82.54 provides a clear distinction for diffuse follicle center lymphoma, enhancing clinical understanding and management.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of lymphomas, improving the accuracy of data collection and treatment tracking. C82.54 provides a clear distinction for diffuse follicle center lymphoma, enhancing clinical understanding and management.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of lymphomas, improving the accuracy of data collection and treatment tracking. C82.54 provides a clear distinction for diffuse follicle center lymphoma, enhancing clinical understanding and management.

Resources

Clinical References

  • •
    American Cancer Society - Lymphoma

Coding & Billing References

  • •
    American Cancer Society - Lymphoma

Frequently Asked Questions

What are the common symptoms of diffuse follicle center lymphoma?

Common symptoms include painless swelling of lymph nodes, fever, night sweats, and unexplained weight loss.