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v1.0.0
ICD-10 Guide
ICD-10 CodesC82.57

C82.57

Billable

Diffuse follicle center lymphoma, spleen

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 C82.57 is a billable code used to indicate a diagnosis of diffuse follicle center lymphoma, spleen.

Key Diagnostic Point:

Diffuse follicle center lymphoma (DFCL) is a subtype of non-Hodgkin lymphoma characterized by the proliferation of neoplastic B-cells within the follicle centers of lymphoid tissue. When localized to the spleen, it presents with splenomegaly and may be associated with systemic symptoms. DFCL is typically classified under the broader category of follicular lymphomas, which are known for their indolent course but can transform into more aggressive forms. Patients may exhibit B-symptoms, including fever, night sweats, and unexplained weight loss, which can indicate disease progression. Diagnosis is confirmed through histopathological examination and immunophenotyping, often requiring a biopsy of the spleen or affected lymph nodes. Treatment options vary based on the stage of the disease and may include watchful waiting, chemotherapy, immunotherapy, or splenectomy. The prognosis depends on various factors, including the patient's overall health, age, and the presence of B-symptoms.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Requires understanding of lymphoma subtypes and staging
  • Differentiation from other types of lymphomas
  • Need for accurate documentation of B-symptoms
  • Potential for transformation to aggressive lymphoma

Audit Risk Factors

  • Inadequate documentation of B-symptoms
  • Misclassification of lymphoma subtype
  • Failure to document staging accurately
  • Inconsistent treatment documentation

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Detailed clinical notes on symptoms, staging, and treatment plans.

Common Clinical Scenarios

Diagnosis and management of lymphoma, treatment response assessments.

Billing Considerations

Ensure accurate documentation of histopathological findings and treatment regimens.

Pathology

Documentation Requirements

Comprehensive reports on biopsy results and immunophenotyping.

Common Clinical Scenarios

Histological evaluation of lymphoid tissues, differential diagnosis of lymphomas.

Billing Considerations

Clear communication of findings to referring physicians for accurate coding.

Coding Guidelines

Inclusion Criteria

Use C82.57 When
  • Follow official ICD
  • CM guidelines for coding neoplasms, ensuring accurate documentation of the primary site and histological type
  • Include staging information when available

Exclusion Criteria

Do NOT use C82.57 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

88305CPT Code

Pathology examination, lymph node biopsy

Clinical Scenario

Used when a biopsy is performed to confirm diagnosis of C82.57.

Documentation Requirements

Pathology report detailing histological findings.

Specialty Considerations

Pathologists must ensure accurate coding based on findings.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 allows for more specific coding of lymphomas, improving the accuracy of diagnosis and treatment tracking. C82.57 provides granularity that aids in clinical decision-making and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 allows for more specific coding of lymphomas, improving the accuracy of diagnosis and treatment tracking. C82.57 provides granularity that aids in clinical decision-making and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    American Cancer Society - Lymphoma

Coding & Billing References

  • •
    American Cancer Society - Lymphoma

Frequently Asked Questions

What are the common treatments for diffuse follicle center lymphoma?

Common treatments include chemotherapy, immunotherapy, and in some cases, splenectomy. The choice of treatment depends on the stage of the disease and the presence of symptoms.