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v1.0.0
ICD-10 Guide
ICD-10 CodesChapter 2: NeoplasmsD21

D21

Billable

Other benign neoplasms of connective and other soft tissue

Chapter 2:Neoplasms

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D21 is a billable code used to indicate a diagnosis of other benign neoplasms of connective and other soft tissue.

Key Diagnostic Point:

D21 encompasses a variety of benign neoplasms that arise from connective tissues and other soft tissues, excluding those specifically classified under other codes. These neoplasms can occur in various locations throughout the body, including the skin, subcutaneous tissue, muscle, and fibrous tissues. Common examples include lipomas, fibromas, and neurofibromas. Clinically, these tumors are typically asymptomatic and may be discovered incidentally during imaging or physical examinations. While benign, they can cause discomfort or functional impairment depending on their size and location. Management often involves observation, surgical excision, or other interventions if symptomatic. Follow-up care is essential to monitor for any changes in size or symptoms, ensuring that any potential complications are addressed promptly. The benign nature of these neoplasms generally leads to a favorable prognosis, but accurate coding is crucial for proper treatment documentation and reimbursement.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of benign neoplasms included under this code
  • Need for precise documentation of tumor location and type
  • Differentiation from malignant neoplasms
  • Potential for overlapping symptoms with other conditions

Audit Risk Factors

  • Inadequate documentation of tumor characteristics
  • Misclassification of benign vs. malignant neoplasms
  • Failure to specify the location of the neoplasm
  • Lack of follow-up documentation

Specialty Focus

Medical Specialties

Oncology

Documentation Requirements

Detailed pathology reports and imaging studies to confirm benign nature.

Common Clinical Scenarios

Management of soft tissue tumors, including surgical excision and follow-up care.

Billing Considerations

Ensure clear documentation of tumor type and location to avoid misclassification.

Dermatology

Documentation Requirements

Photographic evidence and biopsy results for skin lesions.

Common Clinical Scenarios

Evaluation and treatment of cutaneous benign neoplasms.

Billing Considerations

Document any changes in size or symptoms during follow-up visits.

Coding Guidelines

Inclusion Criteria

Use D21 When
  • Follow official coding guidelines that specify the need for accurate documentation of the neoplasm's location, type, and any associated symptoms
  • Ensure that the diagnosis aligns with the treatment provided

Exclusion Criteria

Do NOT use D21 When
No specific exclusions found.

Related CPT Codes

11400CPT Code

Excision, benign lesion

Clinical Scenario

Used when a benign neoplasm is surgically excised.

Documentation Requirements

Document the size, location, and pathology results.

Specialty Considerations

Ensure that the excision is clearly linked to the diagnosis of a benign neoplasm.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of benign neoplasms, improving the accuracy of medical records and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of benign neoplasms, improving the accuracy of medical records and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What types of tumors are classified under D21?

D21 includes various benign neoplasms such as lipomas, fibromas, and neurofibromas, which arise from connective and soft tissues.

How should I document a benign neoplasm for coding?

Documentation should include the type of neoplasm, its location, size, and any symptoms or treatment provided.