Refractory anemia without ring sideroblasts, so stated
ICD-10 D46.0 is a billable code used to indicate a diagnosis of refractory anemia without ring sideroblasts, so stated.
Refractory anemia without ring sideroblasts is a type of anemia characterized by a failure of the bone marrow to produce adequate red blood cells despite the presence of sufficient iron stores. This condition is classified under neoplasms of uncertain behavior, indicating that while it is not classified as a malignancy, it has the potential for progression to more severe forms of hematological disorders. Patients typically present with symptoms of anemia such as fatigue, pallor, and weakness. The absence of ring sideroblasts distinguishes this condition from other forms of refractory anemia, particularly those associated with myelodysplastic syndromes. Diagnosis is often confirmed through bone marrow biopsy, which reveals ineffective erythropoiesis and dysplastic changes in hematopoietic cells. Management may include supportive care, blood transfusions, and in some cases, the use of immunosuppressive therapy. Regular surveillance is crucial due to the risk of progression to acute myeloid leukemia (AML) or other hematological malignancies, necessitating close monitoring of blood counts and clinical symptoms.
Comprehensive documentation of blood counts, bone marrow biopsy results, and treatment plans.
Patients presenting with fatigue and pallor, requiring evaluation of anemia and potential bone marrow disorders.
Close monitoring of blood counts and symptoms to assess for progression to more severe conditions.
Detailed history of the patient's hematological status and any treatments administered.
Patients with a history of refractory anemia being evaluated for potential progression to leukemia.
Understanding the implications of the diagnosis on treatment options and prognosis.
Used to evaluate the patient's blood counts in the context of refractory anemia.
Document the reason for the CBC and any relevant clinical findings.
Hematologists may require additional tests based on CBC results.
Refractory anemia without ring sideroblasts is specifically characterized by ineffective erythropoiesis and the absence of ring sideroblasts, which differentiates it from other anemias that may have different underlying causes or morphological features.