Refractory anemia, unspecified
ICD-10 D46.4 is a billable code used to indicate a diagnosis of refractory anemia, unspecified.
Refractory anemia is a type of anemia that does not respond to standard treatments and is characterized by a persistent low red blood cell count. It is often associated with underlying bone marrow disorders, particularly myelodysplastic syndromes (MDS). Patients with refractory anemia may experience symptoms such as fatigue, weakness, pallor, and increased susceptibility to infections. The condition is classified under neoplasms of uncertain behavior, indicating that while it is not classified as malignant, it has the potential for progression to more severe forms of hematological malignancies. Surveillance is crucial for these patients, as the risk of transformation into acute myeloid leukemia (AML) or other serious conditions necessitates regular monitoring of blood counts and bone marrow status. The unspecified nature of this code indicates that further specification regarding the type or cause of the refractory anemia is not provided, which can complicate treatment and management strategies.
Detailed blood work results, bone marrow biopsy reports, and treatment history.
Patients presenting with persistent anemia despite treatment, requiring evaluation for underlying causes.
Documentation must clearly indicate the refractory nature of the anemia and any associated conditions.
Comprehensive cancer history, treatment plans, and monitoring protocols.
Patients with a history of myelodysplastic syndromes being monitored for progression.
Oncologists must document the potential for transformation into acute leukemia.
Used to monitor hemoglobin levels and overall blood health in patients with refractory anemia.
Must include results of the CBC and any relevant clinical findings.
Hematologists should ensure that the CBC is interpreted in the context of the patient's history.
Refractory anemia is characterized by a lack of response to standard treatments, often indicating an underlying bone marrow disorder, whereas other types of anemia may respond to treatment such as iron supplementation or vitamin B12 injections.
