Sickle-cell thalassemia beta zero with dactylitis
ICD-10 D57.434 is a billable code used to indicate a diagnosis of sickle-cell thalassemia beta zero with dactylitis.
Sickle-cell thalassemia beta zero is a complex hemoglobinopathy resulting from the combination of sickle cell disease and beta-thalassemia. This condition arises from mutations in the HBB gene, leading to the production of abnormal hemoglobin (HbS) and reduced beta-globin chains. Patients with this condition often experience severe hemolytic anemia due to the destruction of sickle-shaped red blood cells, which can lead to various complications. Dactylitis, or hand-foot syndrome, is a common manifestation in children with sickle cell disease, characterized by painful swelling of the fingers and toes due to vaso-occlusive crises. This condition requires careful management to prevent complications such as infections, acute chest syndrome, and stroke. Regular monitoring of hemoglobin levels, pain management, and preventive care, including vaccinations and hydroxyurea therapy, are essential components of treatment. Genetic counseling is also recommended for affected individuals and their families to understand inheritance patterns and reproductive options.
Detailed history of hemolytic episodes, laboratory results including hemoglobin electrophoresis, and management plans.
Management of pain crises, blood transfusions, and monitoring for complications.
Ensure accurate documentation of both sickle cell and thalassemia components for proper coding.
Growth and development assessments, vaccination status, and family history of hemoglobinopathies.
Routine check-ups, management of dactylitis, and education on disease management.
Focus on developmental milestones and psychosocial aspects of living with a chronic condition.
Used for routine blood tests to monitor hemoglobin levels.
Document the reason for blood draw and any relevant clinical findings.
Ensure that the blood draw is linked to the management of sickle-cell thalassemia.
Dactylitis is a common early manifestation of sickle cell disease in children, indicating vaso-occlusive crises and requiring prompt management to prevent further complications.
