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ICD-10 Guide
ICD-10 CodesD57.80

D57.80

Billable

Other sickle-cell disorders without crisis

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D57.80 is a billable code used to indicate a diagnosis of other sickle-cell disorders without crisis.

Key Diagnostic Point:

D57.80 refers to other sickle-cell disorders that do not present with a crisis. Sickle-cell disorders are a group of inherited red blood cell disorders characterized by the presence of abnormal hemoglobin, known as hemoglobin S. These disorders can lead to chronic hemolytic anemia, where red blood cells are destroyed faster than they can be produced. Patients may experience symptoms such as fatigue, pallor, and jaundice due to the anemia. Enzyme deficiencies, such as glucose-6-phosphate dehydrogenase (G6PD) deficiency, can exacerbate hemolytic anemia in these patients. Thalassemias, another group of inherited blood disorders, may coexist with sickle-cell disease, complicating the clinical picture. Genetic factors play a significant role in the manifestation of these disorders, with various mutations leading to different clinical outcomes. It is crucial for healthcare providers to monitor these patients closely for complications, including infections and organ damage, even in the absence of a crisis.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in clinical presentation among patients
  • Need for comprehensive patient history to determine the specific type of sickle-cell disorder
  • Potential overlap with other hemolytic anemias and thalassemias
  • Documentation of genetic testing results

Audit Risk Factors

  • Inadequate documentation of hemolytic anemia symptoms
  • Failure to document genetic testing results
  • Misclassification of acute vs. chronic conditions
  • Lack of clarity in distinguishing between sickle-cell disorders and other anemias

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed patient history, lab results, and genetic testing documentation.

Common Clinical Scenarios

Management of chronic anemia, monitoring for complications, and treatment planning.

Billing Considerations

Ensure accurate differentiation between types of sickle-cell disorders and other hemolytic anemias.

Genetics

Documentation Requirements

Genetic testing results and family history of sickle-cell disorders.

Common Clinical Scenarios

Counseling patients on genetic risks and implications for family planning.

Billing Considerations

Documentation of genetic mutations and their clinical significance is crucial.

Coding Guidelines

Inclusion Criteria

Use D57.80 When
  • According to ICD
  • 10 guidelines, D57
  • 80 should be used when the patient has a diagnosed sickle
  • cell disorder without acute crisis
  • Coders must ensure that the documentation supports the diagnosis and that other related conditions are not present

Exclusion Criteria

Do NOT use D57.80 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

85025CPT Code

Complete blood count (CBC)

Clinical Scenario

Used for routine monitoring of hemoglobin levels in patients with sickle-cell disorders.

Documentation Requirements

Document the reason for the CBC and any relevant patient history.

Specialty Considerations

Hematologists should ensure that the CBC results are interpreted in the context of the patient's sickle-cell disorder.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of sickle-cell disorders, improving the accuracy of diagnoses and treatment plans. D57.80 provides a distinct code for chronic conditions without acute crises, facilitating better patient management.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of sickle-cell disorders, improving the accuracy of diagnoses and treatment plans. D57.80 provides a distinct code for chronic conditions without acute crises, facilitating better patient management.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of sickle-cell disorders, improving the accuracy of diagnoses and treatment plans. D57.80 provides a distinct code for chronic conditions without acute crises, facilitating better patient management.

Resources

Clinical References

  • •
    CDC Sickle Cell Disease

Coding & Billing References

  • •
    CDC Sickle Cell Disease

Frequently Asked Questions

What is the difference between D57.80 and D57.01?

D57.80 is used for chronic sickle-cell disorders without crisis, while D57.01 is for sickle-cell disease with a crisis. Accurate documentation of the patient's condition is essential for proper coding.