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ICD-10 Guide
ICD-10 CodesD57.818

D57.818

Billable

Other sickle-cell disorders with crisis with other specified complication

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D57.818 is a billable code used to indicate a diagnosis of other sickle-cell disorders with crisis with other specified complication.

Key Diagnostic Point:

D57.818 refers to other sickle-cell disorders characterized by crises accompanied by specified complications that do not fall under the more common classifications of sickle cell disease. These disorders can lead to hemolytic anemias, where red blood cells are destroyed faster than they can be produced, often resulting in symptoms such as fatigue, pallor, and jaundice. Enzyme deficiencies, such as glucose-6-phosphate dehydrogenase (G6PD) deficiency, can exacerbate hemolytic anemia during crises. Thalassemias, which are inherited blood disorders affecting hemoglobin production, may also present with similar complications. Genetic factors play a significant role in the manifestation of these disorders, as mutations in the HBB gene can lead to various sickle-cell phenotypes. The clinical management of these patients often involves addressing acute complications, such as pain crises, infections, and organ damage, which can complicate the overall treatment plan. Accurate coding is essential for proper reimbursement and to reflect the complexity of care provided.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of sickle-cell disorders that can be classified under this code
  • Need for precise documentation of complications
  • Differentiation from other hemolytic anemias and genetic disorders
  • Potential for overlapping symptoms with other conditions

Audit Risk Factors

  • Inadequate documentation of complications
  • Misclassification of the type of sickle-cell disorder
  • Failure to document the severity of the crisis
  • Lack of clarity in the relationship between the disorder and the complication

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed patient history, lab results, and treatment plans must be documented.

Common Clinical Scenarios

Management of acute sickle-cell crises, chronic pain management, and transfusion therapy.

Billing Considerations

Ensure that all complications are documented to support the use of D57.818.

Emergency Medicine

Documentation Requirements

Thorough documentation of presenting symptoms, treatment provided, and follow-up care.

Common Clinical Scenarios

Patients presenting with acute pain crises or complications such as acute chest syndrome.

Billing Considerations

Accurate coding of the crisis and any complications is critical for reimbursement.

Coding Guidelines

Inclusion Criteria

Use D57.818 When
  • According to ICD
  • 10 guidelines, D57
  • 818 should be used when a patient presents with a sickle
  • cell disorder and a specified complication that does not fit into other defined categories
  • Coders must ensure that the documentation clearly supports the diagnosis and the associated complications

Exclusion Criteria

Do NOT use D57.818 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

36415CPT Code

Blood transfusion

Clinical Scenario

Used during a crisis to manage severe anemia.

Documentation Requirements

Document the indication for transfusion and patient response.

Specialty Considerations

Hematology specialists should ensure that the transfusion is justified based on lab results.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of sickle-cell disorders, enabling better tracking of complications and outcomes. D57.818 provides a means to capture the complexity of these patients' conditions.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of sickle-cell disorders, enabling better tracking of complications and outcomes. D57.818 provides a means to capture the complexity of these patients' conditions.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of sickle-cell disorders, enabling better tracking of complications and outcomes. D57.818 provides a means to capture the complexity of these patients' conditions.

Resources

Clinical References

  • •
    Sickle Cell Disease Association of America

Coding & Billing References

  • •
    Sickle Cell Disease Association of America

Frequently Asked Questions

What are the common complications associated with D57.818?

Common complications include acute chest syndrome, splenic sequestration, and vaso-occlusive crises, which can lead to severe pain and organ damage.