Other hemolytic-uremic syndrome
ICD-10 D59.39 is a billable code used to indicate a diagnosis of other hemolytic-uremic syndrome.
Other hemolytic-uremic syndrome (HUS) is a serious condition characterized by the triad of hemolytic anemia, acute renal failure, and thrombocytopenia. It can occur due to various underlying causes, including infections, certain medications, and genetic factors. In the context of hemolytic anemias, HUS can be precipitated by enzyme deficiencies such as glucose-6-phosphate dehydrogenase (G6PD) deficiency, which leads to oxidative stress and hemolysis. Thalassemias and sickle cell disease can also contribute to hemolytic processes that may culminate in HUS. Genetic predispositions, such as mutations in the complement system, can lead to atypical HUS, which is often resistant to standard treatments. Clinicians must consider these factors when diagnosing and managing patients with HUS, as the underlying cause significantly influences treatment strategies and prognosis. Accurate coding of D59.39 is essential for proper reimbursement and epidemiological tracking of this complex syndrome.
Detailed lab results, patient history, and treatment plans must be documented.
Patients presenting with unexplained anemia, renal failure, and thrombocytopenia.
Consider genetic testing results and family history in documentation.
Comprehensive renal function tests and urine analysis results are essential.
Patients with acute kidney injury and signs of hemolysis.
Document any renal replacement therapy or interventions performed.
Used to evaluate anemia and thrombocytopenia in suspected HUS.
Document the reason for the CBC and any abnormal findings.
Hematology specialists should ensure all relevant lab results are included.
Common causes include infections (especially E. coli), certain medications, and genetic factors such as complement deficiencies.
