Lymphocytic Variant Hypereosinophilic Syndrome [LHES]
ICD-10 D72.111 is a billable code used to indicate a diagnosis of lymphocytic variant hypereosinophilic syndrome [lhes].
Lymphocytic Variant Hypereosinophilic Syndrome (LHES) is a rare hematological disorder characterized by an elevated eosinophil count in the blood, alongside a predominance of lymphocytes. Patients with LHES often present with symptoms such as fatigue, fever, weight loss, and organ dysfunction due to eosinophilic infiltration. The condition can lead to significant complications, including damage to the heart, lungs, and skin. The etiology of LHES is not fully understood, but it is believed to involve immune dysregulation and may be associated with other hematological disorders, such as chronic lymphocytic leukemia or other white blood cell disorders. Diagnosis typically involves a combination of clinical evaluation, blood tests showing eosinophilia, and exclusion of secondary causes of eosinophilia. Management may include corticosteroids and other immunosuppressive therapies to control eosinophil levels and mitigate organ damage.
Detailed lab results showing eosinophil counts and lymphocyte predominance, clinical notes on symptoms and treatment plans.
Patients presenting with unexplained eosinophilia, fatigue, and organ dysfunction.
Ensure all relevant lab tests are documented to support the diagnosis.
Immunological assessments, history of infections, and response to immunosuppressive therapies.
Patients with recurrent infections or autoimmune symptoms alongside eosinophilia.
Document any immunodeficiencies that may complicate the clinical picture.
Used to monitor eosinophil levels in patients diagnosed with LHES.
Document the reason for the CBC and any relevant clinical findings.
Hematology specialists should ensure that differential counts are clearly reported.
Common symptoms include fatigue, fever, weight loss, and organ dysfunction due to eosinophilic infiltration.
Diagnosis is based on elevated eosinophil counts, clinical symptoms, and exclusion of secondary causes.
