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ICD-10 Guide
ICD-10 CodesD72.819

D72.819

Billable

Decreased white blood cell count, unspecified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D72.819 is a billable code used to indicate a diagnosis of decreased white blood cell count, unspecified.

Key Diagnostic Point:

Decreased white blood cell count, or leukopenia, refers to a condition where the number of white blood cells (WBCs) in the bloodstream is lower than normal. This condition can result from various underlying causes, including bone marrow disorders, autoimmune diseases, infections, and certain medications. Neutropenia, a specific type of leukopenia, is characterized by a decrease in neutrophils, which are crucial for fighting off infections. Patients with decreased WBC counts may experience increased susceptibility to infections, prolonged recovery times, and complications from underlying conditions. The spleen plays a significant role in filtering blood and managing immune responses; disorders of the spleen, such as splenomegaly or hypersplenism, can contribute to decreased WBC counts. Additionally, immunodeficiencies, whether congenital or acquired, can lead to leukopenia, impacting the body's ability to respond to pathogens. Accurate diagnosis and management of decreased WBC counts require a thorough understanding of the underlying causes and appropriate clinical interventions.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying causes leading to decreased WBC count
  • Need for differentiation between types of leukopenia (e.g., neutropenia vs. lymphopenia)
  • Potential overlap with other hematological disorders
  • Documentation requirements for underlying conditions

Audit Risk Factors

  • Inadequate documentation of underlying causes
  • Failure to specify type of leukopenia when applicable
  • Misinterpretation of lab results
  • Inconsistent coding of related conditions

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed lab results, patient history, and treatment plans must be documented.

Common Clinical Scenarios

Patients presenting with unexplained infections, fatigue, or abnormal lab results.

Billing Considerations

Consideration of bone marrow biopsy results and other diagnostic tests is crucial.

Immunology

Documentation Requirements

Thorough documentation of immunodeficiency workup and any associated conditions.

Common Clinical Scenarios

Patients with recurrent infections or known immunodeficiencies.

Billing Considerations

Documentation should include immunoglobulin levels and response to therapies.

Coding Guidelines

Inclusion Criteria

Use D72.819 When
  • Follow official coding guidelines for the selection of codes based on the specificity of the condition
  • Ensure that the documentation supports the diagnosis and includes any relevant lab results

Exclusion Criteria

Do NOT use D72.819 When
  • Exclude conditions that are not directly related to decreased WBC counts

Related ICD-10 Codes

Related CPT Codes

85025CPT Code

Complete blood count (CBC) with differential

Clinical Scenario

Used to evaluate patients presenting with symptoms of infection or fatigue.

Documentation Requirements

Document the reason for the CBC and any relevant clinical findings.

Specialty Considerations

Hematologists may require additional tests based on CBC results.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of leukopenia and related conditions, improving the accuracy of data collection and reimbursement processes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of leukopenia and related conditions, improving the accuracy of data collection and reimbursement processes.

Reimbursement & Billing Impact

reimbursement processes.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common causes of decreased white blood cell count?

Common causes include bone marrow disorders, autoimmune diseases, infections, and the effects of certain medications such as chemotherapy agents.