Leukemoid reaction
ICD-10 D72.823 is a billable code used to indicate a diagnosis of leukemoid reaction.
A leukemoid reaction is a significant increase in white blood cell (WBC) count, often mimicking leukemia, but is typically a response to an underlying condition rather than a malignancy. This reaction can occur due to various stimuli, including infections, inflammation, or stress. In neutropenic patients, the leukemoid reaction may present as a compensatory mechanism to combat infection, leading to elevated WBC counts despite the underlying neutropenia. White blood cell disorders, such as leukopenia or leukocytosis, can complicate the diagnosis and management of leukemoid reactions. Spleen disorders, particularly splenomegaly, can also influence WBC counts and may be associated with leukemoid reactions. Immunodeficiencies, whether congenital or acquired, can predispose individuals to infections that trigger leukemoid reactions. Accurate diagnosis requires a thorough clinical evaluation, including a complete blood count (CBC) and consideration of the patient's clinical history and presenting symptoms.
Detailed lab results, clinical history, and treatment plans.
Patients presenting with elevated WBC counts due to infections or inflammatory conditions.
Ensure clear documentation of the differential diagnosis to avoid confusion with leukemia.
Thorough documentation of infection sources and treatment responses.
Patients with infections leading to leukemoid reactions.
Documenting the relationship between infection and leukocyte elevation is crucial.
Used to evaluate elevated WBC counts in suspected leukemoid reactions.
Document the reason for the CBC and any relevant clinical findings.
Hematology specialists should ensure comprehensive lab interpretation.
A leukemoid reaction is a significant increase in white blood cell count, often in response to infections or other stimuli, and can mimic leukemia but is not a malignancy.
Differentiation is based on clinical context, laboratory findings, and the absence of malignancy indicators in leukemoid reactions.
