Other heparin-induced thrombocytopenia syndrome
ICD-10 D75.828 is a billable code used to indicate a diagnosis of other heparin-induced thrombocytopenia syndrome.
Heparin-induced thrombocytopenia (HIT) is a serious immune-mediated adverse reaction to heparin characterized by a decrease in platelet count and an increased risk of thrombosis. HIT occurs when antibodies form against complexes of heparin and platelet factor 4 (PF4), leading to platelet activation and consumption. The condition can manifest as either type 1 HIT, which is a non-immune response, or type 2 HIT, which is the immune-mediated form that can lead to significant complications such as venous or arterial thrombosis. Patients may present with thrombocytopenia, which is defined as a platelet count of less than 150,000/microL, and may also experience symptoms related to thrombosis, such as swelling, pain, or skin necrosis. The diagnosis is confirmed through clinical assessment and laboratory tests, including the detection of HIT antibodies. Management includes the immediate cessation of heparin and the initiation of alternative anticoagulation therapy. This code specifically captures cases of HIT that do not fall under the more common classifications, thus requiring careful documentation and clinical correlation.
Complete blood counts, platelet counts, and antibody test results must be documented.
Patients presenting with thrombocytopenia after heparin therapy, especially post-surgery or during hospitalization.
Ensure that the clinical context of heparin administration is clearly documented to support the diagnosis.
Thorough history of anticoagulant use and any associated thrombotic events.
Patients with a history of heparin use presenting with unexplained thrombocytopenia.
Document any alternative anticoagulants used and the rationale for their selection.
Used to monitor platelet counts in patients suspected of HIT.
Document the reason for the CBC and any relevant clinical findings.
Hematology specialists should ensure that the CBC is performed in a timely manner to assess for thrombocytopenia.
The primary cause of heparin-induced thrombocytopenia is the formation of antibodies against the heparin-platelet factor 4 complex, leading to platelet activation and consumption.
