Other combined immunodeficiencies
ICD-10 D81.8 is a billable code used to indicate a diagnosis of other combined immunodeficiencies.
Combined immunodeficiencies are a group of disorders characterized by the impaired function of both humoral and cell-mediated immunity. These conditions can lead to increased susceptibility to infections, autoimmune diseases, and malignancies. The term 'other combined immunodeficiencies' encompasses various specific immunodeficiency syndromes that do not fall under the more commonly recognized categories, such as severe combined immunodeficiency (SCID) or Wiskott-Aldrich syndrome. Patients may present with recurrent infections, failure to thrive, and other systemic complications. Diagnosis typically involves immunological testing, including lymphocyte subset analysis, serum immunoglobulin levels, and functional assays to assess immune response. Management may include immunoglobulin replacement therapy, prophylactic antibiotics, and in some cases, hematopoietic stem cell transplantation. The complexity of these conditions arises from their heterogeneous nature and the need for multidisciplinary care, including hematology, immunology, and infectious disease specialists.
Detailed immunological assessment results, including lymphocyte counts and immunoglobulin levels.
Patients presenting with recurrent infections, failure to thrive, or autoimmune manifestations.
Ensure clear documentation of the specific immunodeficiency type and associated complications.
Complete blood counts, bone marrow biopsy results, and any relevant genetic testing.
Patients with hematologic abnormalities and signs of immunodeficiency.
Document any hematologic conditions that may coexist with immunodeficiency.
Used for obtaining blood samples for immunological testing.
Document the reason for blood collection and any relevant patient history.
Ensure that the specialty performing the test is clearly documented.
Common symptoms include recurrent infections, failure to thrive, autoimmune disorders, and increased susceptibility to certain cancers.