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v1.0.0
ICD-10 Guide
ICD-10 CodesD82.8

D82.8

Billable

Immunodeficiency associated with other specified major defects

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D82.8 is a billable code used to indicate a diagnosis of immunodeficiency associated with other specified major defects.

Key Diagnostic Point:

D82.8 refers to immunodeficiency disorders that are associated with other specified major defects in the immune system. These conditions can arise from genetic mutations or environmental factors that compromise the immune response, leading to increased susceptibility to infections and other complications. Patients may present with recurrent infections, autoimmune disorders, or hematologic abnormalities. The immunodeficiency may be secondary to other underlying conditions, such as hematologic malignancies or congenital defects affecting blood and blood-forming organs. Accurate diagnosis often requires a thorough clinical evaluation, including laboratory tests to assess immune function and identify specific defects. Management may involve immunoglobulin replacement therapy, prophylactic antibiotics, or treatment of the underlying condition. Understanding the nuances of this code is crucial for proper documentation and coding, as it encompasses a range of disorders that may not be immediately apparent.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying conditions that can lead to immunodeficiency.
  • Need for comprehensive clinical documentation to support the diagnosis.
  • Potential overlap with other immunodeficiency codes.
  • Variability in clinical presentation and laboratory findings.

Audit Risk Factors

  • Inadequate documentation of the underlying condition.
  • Failure to specify the type of immunodeficiency.
  • Misclassification of the condition due to overlapping symptoms.
  • Lack of supporting laboratory results.

Specialty Focus

Medical Specialties

Immunology

Documentation Requirements

Detailed immunological assessments, including laboratory results and clinical history.

Common Clinical Scenarios

Patients with recurrent infections, autoimmune disorders, or unexplained hematologic abnormalities.

Billing Considerations

Ensure that all relevant tests and specialist consultations are documented to support the diagnosis.

Hematology

Documentation Requirements

Complete blood counts, bone marrow biopsies, and genetic testing results.

Common Clinical Scenarios

Patients with hematologic malignancies presenting with immunodeficiency symptoms.

Billing Considerations

Document any hematologic conditions that may contribute to the immunodeficiency.

Coding Guidelines

Inclusion Criteria

Use D82.8 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the diagnosis is supported by clinical documentation
  • Include any relevant laboratory findings and specify the underlying conditions contributing to the immunodeficiency

Exclusion Criteria

Do NOT use D82.8 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

36415CPT Code

Collection of venous blood by venipuncture

Clinical Scenario

Used for laboratory tests to assess immune function.

Documentation Requirements

Document the reason for blood collection and any relevant clinical history.

Specialty Considerations

Ensure that the specialty performing the test is noted.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of immunodeficiency disorders, improving the ability to capture the complexity of these conditions and their associated complications.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of immunodeficiency disorders, improving the ability to capture the complexity of these conditions and their associated complications.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of immunodeficiency disorders, improving the ability to capture the complexity of these conditions and their associated complications.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What types of conditions are included under D82.8?

D82.8 includes various immunodeficiencies associated with other specified major defects, such as genetic mutations affecting immune function, hematologic malignancies, and autoimmune disorders.