Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
ICD-10 D83.0 is a billable code used to indicate a diagnosis of common variable immunodeficiency with predominant abnormalities of b-cell numbers and function.
Common Variable Immunodeficiency (CVID) is a primary immunodeficiency disorder characterized by low levels of immunoglobulins and an increased susceptibility to infections. Patients with CVID often exhibit significant abnormalities in B-cell numbers and function, leading to impaired antibody production. This condition typically presents in late childhood or adulthood and is associated with recurrent bacterial infections, particularly of the respiratory and gastrointestinal tracts. In addition to infections, patients may experience autoimmune disorders, lymphoproliferative diseases, and an increased risk of malignancies. The diagnosis of CVID is based on clinical history, laboratory findings, and the exclusion of other causes of hypogammaglobulinemia. Management often includes immunoglobulin replacement therapy and treatment of infections and associated complications. Regular monitoring and supportive care are essential to improve the quality of life and reduce morbidity in affected individuals.
Detailed immunological assessment results, including immunoglobulin levels and B-cell counts.
Patients presenting with recurrent infections, autoimmune manifestations, or unexplained hypogammaglobulinemia.
Ensure comprehensive documentation of all laboratory findings and treatment plans.
Complete blood counts, bone marrow biopsy results if applicable, and any hematologic complications.
Patients with CVID presenting with anemia, thrombocytopenia, or lymphoproliferative disorders.
Document any hematologic abnormalities and their management to support coding.
Used for obtaining blood samples to assess immunoglobulin levels.
Document the reason for blood draw and any relevant clinical history.
Ensure that the immunology specialty is aware of the blood collection for accurate interpretation.
Common symptoms include recurrent infections, particularly respiratory and gastrointestinal infections, autoimmune disorders, and lymphadenopathy. Patients may also experience chronic fatigue and other systemic symptoms.
