Other common variable immunodeficiencies
ICD-10 D83.8 is a billable code used to indicate a diagnosis of other common variable immunodeficiencies.
Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder characterized by low levels of immunoglobulins and an increased susceptibility to infections. Patients with CVID often present with recurrent bacterial infections, particularly of the respiratory and gastrointestinal tracts. The condition can also lead to autoimmune disorders, lymphoproliferative diseases, and an increased risk of malignancies. The etiology of CVID is heterogeneous, with both genetic and environmental factors contributing to its development. Diagnosis typically involves measuring serum immunoglobulin levels, assessing specific antibody responses, and ruling out other causes of hypogammaglobulinemia. Management includes immunoglobulin replacement therapy and treatment of infections, as well as monitoring for associated complications such as bronchiectasis and lymphomas. The complexity of CVID lies in its variable presentation and the need for a multidisciplinary approach to care, including immunology, infectious disease, and hematology specialists.
Detailed immunological assessment results, including immunoglobulin levels and specific antibody responses.
Patients presenting with recurrent infections, autoimmune disorders, or unexplained hypogammaglobulinemia.
Documentation should clearly outline the diagnostic criteria met for CVID and any associated conditions.
Complete blood counts, bone marrow biopsy results if applicable, and documentation of any hematologic malignancies.
Patients with CVID who develop lymphoproliferative disorders or other hematologic complications.
Ensure that any hematologic conditions are clearly linked to the primary diagnosis of CVID.
Used for patients receiving immunoglobulin replacement therapy.
Document the patient's immunoglobulin levels and treatment plan.
Immunology specialists should ensure that the therapy is justified based on the patient's clinical status.
Common symptoms include recurrent infections, particularly respiratory and gastrointestinal, autoimmune disorders, and chronic fatigue. Patients may also experience lymphadenopathy and splenomegaly.
