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v1.0.0
ICD-10 Guide
ICD-10 CodesD84.89

D84.89

Billable

Other immunodeficiencies

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D84.89 is a billable code used to indicate a diagnosis of other immunodeficiencies.

Key Diagnostic Point:

D84.89 refers to a category of immunodeficiencies that do not fall under the more specific classifications of primary or secondary immunodeficiencies. These conditions can arise from various etiologies, including genetic mutations, environmental factors, or as a consequence of other diseases. Patients with D84.89 may present with recurrent infections, autoimmune disorders, or malignancies due to their compromised immune systems. The immunodeficiency can affect various components of the immune system, including humoral immunity, cell-mediated immunity, and innate immune responses. Clinicians must conduct thorough evaluations to identify the underlying causes, which may include hematologic disorders such as lymphoproliferative diseases or bone marrow pathologies. Treatment often involves managing infections, immunoglobulin replacement therapy, or addressing the underlying condition contributing to the immunodeficiency. Accurate coding is essential for proper reimbursement and to ensure that patients receive appropriate care.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying causes leading to immunodeficiency
  • Overlap with other immunodeficiency codes
  • Need for detailed clinical documentation to support diagnosis
  • Potential for misclassification with related hematologic disorders

Audit Risk Factors

  • Inadequate documentation of the underlying cause of immunodeficiency
  • Misuse of related codes leading to upcoding or downcoding
  • Failure to document recurrent infections or complications
  • Inconsistent coding across different encounters

Specialty Focus

Medical Specialties

Hematology

Documentation Requirements

Detailed history of hematologic conditions, laboratory results, and treatment plans.

Common Clinical Scenarios

Patients with unexplained recurrent infections or hematologic malignancies.

Billing Considerations

Ensure that all relevant lab results and clinical findings are documented to support the diagnosis.

Immunology

Documentation Requirements

Comprehensive immunological assessments, including specific antibody responses and T-cell function tests.

Common Clinical Scenarios

Patients presenting with autoimmune disorders or severe allergies alongside immunodeficiency.

Billing Considerations

Document any genetic testing or family history of immunodeficiency to clarify the diagnosis.

Coding Guidelines

Inclusion Criteria

Use D84.89 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the diagnosis is supported by clinical documentation
  • 89 should be used when no more specific code applies, and the underlying cause of the immunodeficiency is documented

Exclusion Criteria

Do NOT use D84.89 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

36415CPT Code

Collection of venous blood by venipuncture

Clinical Scenario

Used for laboratory tests to evaluate immune function.

Documentation Requirements

Document the reason for blood draw and any relevant clinical history.

Specialty Considerations

Ensure that the specialty performing the test is noted in the documentation.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of immunodeficiencies, improving the ability to capture the complexity of these conditions. D84.89 provides a necessary code for cases that do not fit into more specific categories, ensuring appropriate care and reimbursement.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of immunodeficiencies, improving the ability to capture the complexity of these conditions. D84.89 provides a necessary code for cases that do not fit into more specific categories, ensuring appropriate care and reimbursement.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common causes of D84.89?

D84.89 can be caused by genetic mutations, environmental factors, or secondary to other diseases such as malignancies or autoimmune disorders.

How do I differentiate D84.89 from other immunodeficiencies?

D84.89 is used when no more specific immunodeficiency code applies. It is essential to review the clinical documentation to identify the underlying cause.