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ICD-10 Guide
ICD-10 CodesD89.811

D89.811

Billable

Chronic graft-versus-host disease

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 D89.811 is a billable code used to indicate a diagnosis of chronic graft-versus-host disease.

Key Diagnostic Point:

Chronic graft-versus-host disease (cGVHD) is a serious complication that can occur after allogeneic hematopoietic stem cell transplantation (HSCT). It arises when donor immune cells attack the recipient's tissues, leading to a range of symptoms that can affect multiple organ systems. Clinically, cGVHD can manifest in the skin, liver, gastrointestinal tract, lungs, and eyes, among other areas. Symptoms may include skin rashes, jaundice, dry eyes, and gastrointestinal disturbances. The condition can develop months to years after transplantation, distinguishing it from acute graft-versus-host disease, which typically occurs within the first 100 days post-transplant. Diagnosis is based on clinical findings, patient history, and sometimes biopsy of affected tissues. Management often involves immunosuppressive therapies to mitigate the immune response, and ongoing monitoring is essential to manage complications and improve quality of life for affected patients.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Requires detailed documentation of symptoms and affected organ systems.
  • Differentiation from acute graft-versus-host disease can be challenging.
  • Management often involves multiple specialties, complicating coding.
  • Long-term follow-up and monitoring may lead to additional coding considerations.

Audit Risk Factors

  • Inadequate documentation of the onset and duration of symptoms.
  • Failure to specify affected organ systems.
  • Misclassification of acute versus chronic forms of the disease.
  • Lack of follow-up documentation to support ongoing treatment.

Specialty Focus

Medical Specialties

Hematology/Oncology

Documentation Requirements

Detailed clinical notes on the patient's transplant history, symptoms, and treatment plans.

Common Clinical Scenarios

Patients presenting with skin rashes, liver dysfunction, or gastrointestinal symptoms post-transplant.

Billing Considerations

Close collaboration with transplant teams is essential for accurate coding.

Dermatology

Documentation Requirements

Photographic evidence of skin manifestations and detailed descriptions of lesions.

Common Clinical Scenarios

Patients with skin involvement requiring dermatological intervention.

Billing Considerations

Documentation must clearly link skin findings to cGVHD.

Coding Guidelines

Inclusion Criteria

Use D89.811 When
  • According to ICD
  • 10 guidelines, D89
  • 811 should be used when chronic graft
  • versus
  • host disease is confirmed, and documentation must reflect the chronic nature of the condition

Exclusion Criteria

Do NOT use D89.811 When
  • Exclusion criteria include acute forms of the disease and other unrelated conditions

Related ICD-10 Codes

Related CPT Codes

96413CPT Code

Chemotherapy administration, intravenous

Clinical Scenario

Used when a patient with cGVHD requires chemotherapy for management.

Documentation Requirements

Document the reason for chemotherapy and the patient's cGVHD status.

Specialty Considerations

Oncology specialists should ensure accurate coding of the treatment plan.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of chronic graft-versus-host disease, improving the ability to track and manage this complex condition. It has also enhanced the granularity of data for research and treatment outcomes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of chronic graft-versus-host disease, improving the ability to track and manage this complex condition. It has also enhanced the granularity of data for research and treatment outcomes.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of chronic graft-versus-host disease, improving the ability to track and manage this complex condition. It has also enhanced the granularity of data for research and treatment outcomes.

Resources

Clinical References

  • •
    Chronic Graft-Versus-Host Disease: A Guide for Clinicians

Coding & Billing References

  • •
    Chronic Graft-Versus-Host Disease: A Guide for Clinicians

Frequently Asked Questions

What is the difference between acute and chronic graft-versus-host disease?

Acute graft-versus-host disease typically occurs within the first 100 days post-transplant and presents with more severe symptoms, while chronic graft-versus-host disease can develop later and often involves a broader range of symptoms affecting multiple organ systems.