Hypothyroidism due to medicaments and other exogenous substances
ICD-10 E03.2 is a billable code used to indicate a diagnosis of hypothyroidism due to medicaments and other exogenous substances.
Hypothyroidism due to medicaments and other exogenous substances refers to a condition where the thyroid gland is underactive due to external factors, particularly medications or substances that inhibit thyroid function. Common medications that can lead to this condition include lithium, amiodarone, and certain antithyroid drugs. The pathophysiology involves the interference of these substances with thyroid hormone synthesis or secretion, leading to decreased levels of thyroid hormones in the bloodstream. Clinically, patients may present with symptoms such as fatigue, weight gain, cold intolerance, and depression. Diagnosis typically involves thyroid function tests, including serum TSH (Thyroid Stimulating Hormone) and free T4 levels, which help confirm the underactive thyroid status. Management may require discontinuation of the offending agent and initiation of thyroid hormone replacement therapy, depending on the severity of the hypothyroidism. Regular monitoring of thyroid function tests is essential to ensure appropriate management and adjustment of therapy.
Detailed medication history, lab results, and clinical symptoms.
Patients presenting with unexplained fatigue or weight gain who are on medications known to affect thyroid function.
Endocrinologists must ensure that all medications are documented and that the relationship between medication use and thyroid function is clearly established.
Comprehensive patient history, including medication review and symptom assessment.
Routine check-ups where patients report new symptoms after starting a new medication.
Primary care providers should be vigilant about the potential side effects of medications prescribed and their impact on thyroid function.
Used to evaluate thyroid function in patients suspected of having hypothyroidism.
Document the reason for the test and any relevant clinical findings.
Endocrinologists may require more detailed documentation of thyroid function tests.
Common medications include lithium, amiodarone, and certain antithyroid drugs. It's important to review the patient's medication history to identify potential causes.
