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ICD-10 Guide
ICD-10 CodesE05.01

E05.01

Billable

Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E05.01 is a billable code used to indicate a diagnosis of thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm.

Key Diagnostic Point:

Thyrotoxicosis with diffuse goiter and thyrotoxic crisis, also known as thyroid storm, is a life-threatening condition characterized by an extreme overproduction of thyroid hormones. This condition typically arises in patients with pre-existing hyperthyroidism, often due to Graves' disease, and is exacerbated by stressors such as infection, surgery, or trauma. Clinically, patients may present with symptoms including fever, tachycardia, hypertension, agitation, and altered mental status. The diffuse goiter indicates an enlargement of the thyroid gland, which is often palpable and may be associated with a hypermetabolic state. Diagnosis is confirmed through thyroid function tests showing elevated levels of free T4 and T3, alongside suppressed TSH levels. Immediate treatment is critical and may involve antithyroid medications, beta-blockers, and supportive care to stabilize the patient. Understanding the nuances of this condition is essential for accurate coding and appropriate management.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Requires understanding of thyroid function tests and their implications.
  • Differentiation from other forms of hyperthyroidism and thyroid disorders.
  • Need for precise documentation of symptoms and clinical findings.
  • Potential for overlapping diagnoses in patients with multiple endocrine disorders.

Audit Risk Factors

  • Inadequate documentation of acute symptoms and their severity.
  • Failure to document the underlying cause of thyrotoxicosis.
  • Misclassification of the condition as non-acute.
  • Lack of clarity in the treatment plan and response to therapy.

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Thorough documentation of thyroid function tests, clinical symptoms, and treatment plans.

Common Clinical Scenarios

Management of patients presenting with acute thyrotoxicosis, monitoring of thyroid hormone levels, and treatment adjustments.

Billing Considerations

Ensure that all relevant lab results and clinical observations are documented to support the diagnosis.

Emergency Medicine

Documentation Requirements

Detailed notes on patient presentation, vital signs, and immediate interventions performed.

Common Clinical Scenarios

Patients presenting with symptoms of thyroid storm requiring rapid assessment and stabilization.

Billing Considerations

Document the timeline of symptom onset and interventions to establish the urgency of the condition.

Coding Guidelines

Inclusion Criteria

Use E05.01 When
  • According to ICD
  • CM guidelines, E05
  • 01 should be used when there is clear documentation of thyrotoxicosis with diffuse goiter and evidence of a thyrotoxic crisis
  • It is essential to ensure that the diagnosis is supported by clinical findings and laboratory results, including elevated thyroid hormone levels and suppressed TSH

Exclusion Criteria

Do NOT use E05.01 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

84443CPT Code

Thyroid function tests

Clinical Scenario

Used to confirm diagnosis of thyrotoxicosis in patients presenting with symptoms.

Documentation Requirements

Document the rationale for testing and results to support diagnosis.

Specialty Considerations

Endocrinologists should ensure comprehensive lab panels are ordered.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like thyrotoxicosis, improving the accuracy of diagnoses and treatment plans. E05.01 provides a clear distinction for cases involving a thyrotoxic crisis, which is critical for appropriate management and reimbursement.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like thyrotoxicosis, improving the accuracy of diagnoses and treatment plans. E05.01 provides a clear distinction for cases involving a thyrotoxic crisis, which is critical for appropriate management and reimbursement.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    American Thyroid Association Guidelines

Coding & Billing References

  • •
    American Thyroid Association Guidelines

Frequently Asked Questions

What are the key symptoms of thyrotoxicosis with crisis?

Key symptoms include fever, tachycardia, agitation, confusion, and gastrointestinal disturbances. Patients may also exhibit signs of hypermetabolism such as weight loss and heat intolerance.