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ICD-10 Guide
ICD-10 CodesE05.10

E05.10

Billable

Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E05.10 is a billable code used to indicate a diagnosis of thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm.

Key Diagnostic Point:

Thyrotoxicosis with a toxic single thyroid nodule is a condition characterized by excessive thyroid hormone production due to a hyperfunctioning nodule within the thyroid gland. This condition typically presents with symptoms of hyperthyroidism, such as weight loss, increased appetite, heat intolerance, palpitations, and anxiety. Unlike thyrotoxic crisis or storm, which is a life-threatening exacerbation of hyperthyroidism, E05.10 indicates a more stable state of thyrotoxicosis. The toxic nodule is often a benign adenoma that autonomously secretes thyroid hormones, leading to suppressed levels of thyroid-stimulating hormone (TSH) due to negative feedback. Diagnosis is confirmed through thyroid function tests, including serum TSH, free T4, and total T3 levels, along with imaging studies such as a thyroid scan to assess the nodule's activity. Management may involve antithyroid medications, radioactive iodine therapy, or surgical intervention depending on the nodule's characteristics and the patient's overall health.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between toxic and non-toxic nodules
  • Understanding the nuances of hyperthyroid symptoms
  • Interpreting thyroid function tests accurately
  • Recognizing the absence of thyrotoxic crisis

Audit Risk Factors

  • Inadequate documentation of the nodule's characteristics
  • Misclassification of thyrotoxic crisis
  • Failure to document thyroid function test results
  • Inconsistent coding of related conditions

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Thorough documentation of thyroid function tests, imaging results, and treatment plans.

Common Clinical Scenarios

Patients presenting with symptoms of hyperthyroidism and confirmed toxic nodules.

Billing Considerations

Ensure clear differentiation between toxic nodules and other thyroid disorders.

Primary Care

Documentation Requirements

Comprehensive patient history, symptom assessment, and referral notes to specialists.

Common Clinical Scenarios

Initial evaluation of hyperthyroid symptoms leading to referral for further management.

Billing Considerations

Documenting the patient's response to initial treatment and follow-up care.

Coding Guidelines

Inclusion Criteria

Use E05.10 When
  • Follow ICD
  • Include relevant lab results and imaging studies in the medical record

Exclusion Criteria

Do NOT use E05.10 When
  • CM guidelines for coding thyroid disorders, ensuring accurate documentation of the toxic nodule and exclusion of crisis conditions

Related ICD-10 Codes

Related CPT Codes

85025CPT Code

Thyroid function tests

Clinical Scenario

Used to monitor thyroid hormone levels in patients with toxic nodules.

Documentation Requirements

Document the rationale for testing and results.

Specialty Considerations

Endocrinologists may require more detailed lab results for treatment planning.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of thyroid disorders, improving the accuracy of diagnoses and treatment plans. E05.10 provides a clear distinction for cases involving toxic nodules, enhancing clinical data quality.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of thyroid disorders, improving the accuracy of diagnoses and treatment plans. E05.10 provides a clear distinction for cases involving toxic nodules, enhancing clinical data quality.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of thyroid disorders, improving the accuracy of diagnoses and treatment plans. E05.10 provides a clear distinction for cases involving toxic nodules, enhancing clinical data quality.

Resources

Clinical References

  • •
    American Thyroid Association Guidelines

Coding & Billing References

  • •
    American Thyroid Association Guidelines

Frequently Asked Questions

What symptoms indicate the need for coding E05.10?

Symptoms such as unexplained weight loss, increased heart rate, anxiety, and heat intolerance may indicate thyrotoxicosis with a toxic nodule, warranting the use of E05.10.