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ICD-10 Guide
ICD-10 CodesE05.3

E05.3

Billable

Thyrotoxicosis from ectopic thyroid tissue

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E05.3 is a billable code used to indicate a diagnosis of thyrotoxicosis from ectopic thyroid tissue.

Key Diagnostic Point:

Thyrotoxicosis from ectopic thyroid tissue refers to a condition where thyroid hormone is produced by thyroid tissue that is located outside of its normal anatomical location. This ectopic tissue can lead to hyperthyroidism, characterized by an excess of thyroid hormones in the bloodstream, resulting in symptoms such as weight loss, increased heart rate, anxiety, and heat intolerance. Ectopic thyroid tissue may arise due to developmental anomalies during embryogenesis, where thyroid tissue fails to migrate to its usual position in the neck. Diagnosis typically involves thyroid function tests, which reveal elevated levels of thyroxine (T4) and triiodothyronine (T3), alongside suppressed thyroid-stimulating hormone (TSH) levels. Imaging studies, such as ultrasound or scintigraphy, may be utilized to locate the ectopic tissue. Management may include antithyroid medications, radioactive iodine therapy, or surgical intervention, depending on the severity of the thyrotoxicosis and the patient's overall health status.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variability in presentation of ectopic thyroid tissue
  • Need for precise documentation of thyroid function tests
  • Differential diagnosis with other forms of hyperthyroidism
  • Potential for misdiagnosis if ectopic tissue is not identified

Audit Risk Factors

  • Inadequate documentation of ectopic tissue location
  • Failure to document thyroid function test results
  • Misclassification of hyperthyroidism type
  • Lack of clarity in treatment plans

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed thyroid function test results, imaging studies, and treatment plans must be documented.

Common Clinical Scenarios

Patients presenting with symptoms of hyperthyroidism and abnormal thyroid function tests.

Billing Considerations

Endocrinologists must ensure that the presence of ectopic thyroid tissue is clearly documented to avoid misdiagnosis.

Surgery

Documentation Requirements

Surgical reports must specify the location and nature of ectopic thyroid tissue if surgical intervention is performed.

Common Clinical Scenarios

Patients requiring surgical removal of ectopic thyroid tissue due to severe thyrotoxicosis.

Billing Considerations

Surgeons should document the rationale for surgery and any preoperative imaging findings.

Coding Guidelines

Inclusion Criteria

Use E05.3 When
  • Follow the official ICD
  • CM coding guidelines for accurate coding of thyrotoxicosis
  • Ensure that documentation supports the diagnosis of thyrotoxicosis from ectopic thyroid tissue, including results from thyroid function tests and imaging studies

Exclusion Criteria

Do NOT use E05.3 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

84443CPT Code

Thyroid stimulating hormone (TSH)

Clinical Scenario

Used to evaluate thyroid function in patients suspected of having thyrotoxicosis.

Documentation Requirements

Document the reason for the test and the results.

Specialty Considerations

Endocrinologists should ensure that TSH levels are interpreted in the context of thyroid hormone levels.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of conditions like thyrotoxicosis from ectopic thyroid tissue, improving the accuracy of diagnoses and treatment plans.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of conditions like thyrotoxicosis from ectopic thyroid tissue, improving the accuracy of diagnoses and treatment plans.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of conditions like thyrotoxicosis from ectopic thyroid tissue, improving the accuracy of diagnoses and treatment plans.

Resources

Clinical References

  • •
    American Thyroid Association Guidelines

Coding & Billing References

  • •
    American Thyroid Association Guidelines

Frequently Asked Questions

What is the primary cause of thyrotoxicosis from ectopic thyroid tissue?

The primary cause is the presence of thyroid tissue that has not migrated to its normal location during embryonic development, leading to autonomous hormone production.