Sick-euthyroid syndrome
ICD-10 E07.81 is a billable code used to indicate a diagnosis of sick-euthyroid syndrome.
Sick-euthyroid syndrome, also known as non-thyroidal illness syndrome, is a condition characterized by abnormal thyroid function tests in patients who are not suffering from intrinsic thyroid disease. This syndrome often occurs in the context of acute or chronic illness, such as infections, trauma, or systemic diseases. Patients typically present with low levels of thyroxine (T4) and triiodothyronine (T3), while thyroid-stimulating hormone (TSH) levels may remain normal or low. The underlying mechanism is thought to involve alterations in the hypothalamic-pituitary-thyroid axis due to the illness, leading to decreased conversion of T4 to T3 and increased peripheral metabolism of thyroid hormones. It is crucial to differentiate sick-euthyroid syndrome from true thyroid disorders, such as hypothyroidism or hyperthyroidism, as the management of these conditions differs significantly. Diagnosis is primarily based on clinical context and thyroid function tests, and treatment typically focuses on addressing the underlying illness rather than thyroid hormone replacement.
Thorough documentation of thyroid function tests, patient history, and clinical context.
Patients with chronic illnesses presenting with abnormal thyroid function tests.
Endocrinologists must ensure that the diagnosis of sick-euthyroid syndrome is supported by comprehensive lab results and clinical findings.
Detailed patient history and documentation of any acute or chronic illnesses affecting thyroid function.
Hospitalized patients with systemic illnesses showing altered thyroid hormone levels.
Internal medicine physicians should be aware of the implications of sick-euthyroid syndrome in the context of overall patient management.
Used to evaluate thyroid function in patients suspected of having sick-euthyroid syndrome.
Document the reason for the test and any relevant clinical findings.
Endocrinologists should correlate TSH results with clinical context.
Ordered to assess thyroid hormone levels in patients with systemic illness.
Document the patient's clinical status and any underlying conditions.
Internal medicine specialists should ensure comprehensive documentation.
Sick-euthyroid syndrome is a condition where thyroid function tests are abnormal due to non-thyroidal illness, without intrinsic thyroid disease.
Diagnosis is based on abnormal thyroid function tests in the context of an underlying illness, requiring careful clinical evaluation.