Other disorders of pancreatic internal secretion
Chapter 4:Endocrine, nutritional and metabolic diseases
ICD-10 E16 is a billable code used to indicate a diagnosis of other disorders of pancreatic internal secretion.
E16 encompasses a variety of conditions related to the dysfunction of pancreatic internal secretion, particularly those affecting insulin and glucose metabolism. This includes disorders such as hyperinsulinism, where excessive insulin secretion leads to hypoglycemia, and pancreatic islet disorders that disrupt normal glucose regulation. Patients may present with symptoms ranging from recurrent hypoglycemic episodes, characterized by sweating, palpitations, and confusion, to hyperglycemic states if insulin secretion is insufficient. The underlying pathophysiology often involves abnormalities in pancreatic islet cell function, which can be due to genetic factors, autoimmune processes, or other metabolic disturbances. Accurate diagnosis typically requires a combination of clinical evaluation, biochemical testing, and imaging studies to assess pancreatic function and structure. Understanding these disorders is crucial for effective management, which may include dietary modifications, medication, or surgical interventions in severe cases.
Detailed patient history, lab results, and treatment plans must be documented.
Patients presenting with unexplained hypoglycemia or hyperinsulinism.
Endocrinologists should ensure that all relevant tests are documented to support the diagnosis.
Comprehensive assessment of metabolic status and any comorbid conditions.
Management of patients with diabetes and concurrent pancreatic disorders.
Internal medicine physicians should document any referrals to specialists for further evaluation.
Used to confirm hypoglycemia in patients suspected of having E16.
Document the reason for testing and results.
Endocrinologists should correlate lab results with clinical findings.
E16 includes various disorders related to pancreatic internal secretion, such as hyperinsulinism and other pancreatic islet disorders affecting glucose metabolism.
