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ICD-10 Guide
ICD-10 CodesE22.0

E22.0

Billable

Acromegaly and pituitary gigantism

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E22.0 is a billable code used to indicate a diagnosis of acromegaly and pituitary gigantism.

Key Diagnostic Point:

Acromegaly is a hormonal disorder that results from excess growth hormone (GH) in the body, typically due to a benign tumor on the pituitary gland known as an adenoma. This condition leads to the enlargement of bones and tissues, particularly in the face, hands, and feet. Patients may experience a range of symptoms including joint pain, thickened skin, and increased sweating. Pituitary gigantism, on the other hand, occurs in children and adolescents before the closure of growth plates, resulting in excessive height and growth. Both conditions are linked to dysregulation of the endocrine system, particularly involving the pituitary gland, which plays a crucial role in hormone production and regulation. The overproduction of GH can also lead to secondary complications such as diabetes mellitus, hypertension, and cardiovascular disease. Diagnosis typically involves measuring serum GH levels and conducting imaging studies like MRI to identify pituitary tumors. Treatment options may include surgical removal of the tumor, medication to inhibit GH production, or radiation therapy.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between acromegaly and pituitary gigantism based on age of onset.
  • Understanding the implications of hormone imbalances and related endocrine disorders.
  • Navigating the documentation requirements for various specialties involved in treatment.
  • Identifying co-morbid conditions that may complicate coding.

Audit Risk Factors

  • Inadequate documentation of growth hormone levels.
  • Failure to document the presence of pituitary adenomas.
  • Misclassification of acromegaly as a different endocrine disorder.
  • Lack of detailed clinical history regarding symptoms.

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed patient history, lab results, imaging studies, and treatment plans.

Common Clinical Scenarios

Diagnosis and management of acromegaly, monitoring of growth hormone levels, and treatment of associated conditions.

Billing Considerations

Endocrinologists must ensure comprehensive documentation of hormone levels and symptoms to support the diagnosis.

Surgery

Documentation Requirements

Operative reports, pre-operative assessments, and post-operative follow-ups.

Common Clinical Scenarios

Surgical intervention for pituitary adenomas causing acromegaly.

Billing Considerations

Surgeons should document the extent of tumor removal and any complications to support coding.

Coding Guidelines

Inclusion Criteria

Use E22.0 When
  • Follow the official ICD
  • CM coding guidelines for endocrine disorders
  • Ensure accurate documentation of the diagnosis, including the presence of any related conditions

Exclusion Criteria

Do NOT use E22.0 When
  • Exclude conditions that do not meet the criteria for E22

Related ICD-10 Codes

Related CPT Codes

60300CPT Code

Transsphenoidal resection of pituitary tumor

Clinical Scenario

Used in cases where surgical intervention is required for pituitary adenomas causing acromegaly.

Documentation Requirements

Operative report detailing the procedure and findings.

Specialty Considerations

Endocrinologists and neurosurgeons must collaborate on documentation to ensure accurate coding.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of acromegaly and related conditions, improving the accuracy of diagnoses and treatment tracking. This specificity aids in better patient management and resource allocation.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of acromegaly and related conditions, improving the accuracy of diagnoses and treatment tracking. This specificity aids in better patient management and resource allocation.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of acromegaly and related conditions, improving the accuracy of diagnoses and treatment tracking. This specificity aids in better patient management and resource allocation.

Resources

Clinical References

  • •
    Acromegaly: A Guide for Patients and Families

Coding & Billing References

  • •
    Acromegaly: A Guide for Patients and Families

Frequently Asked Questions

What are the primary symptoms of acromegaly?

Common symptoms include enlarged hands and feet, facial changes, joint pain, and increased sweating. Patients may also experience complications such as diabetes and hypertension.