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ICD-10 Guide
ICD-10 CodesChapter 4: Endocrine, nutritional and metabolic diseasesE23

E23

Billable

Hypofunction and other disorders of the pituitary gland

Chapter 4:Endocrine, nutritional and metabolic diseases

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E23 is a billable code used to indicate a diagnosis of hypofunction and other disorders of the pituitary gland.

Key Diagnostic Point:

Hypofunction and other disorders of the pituitary gland encompass a range of conditions characterized by insufficient hormone production from the pituitary gland, which is a crucial endocrine organ located at the base of the brain. This gland regulates various hormonal functions by releasing hormones that control other endocrine glands, including the adrenal glands, thyroid, and gonads. Disorders such as hypopituitarism can lead to deficiencies in growth hormone, thyroid-stimulating hormone, adrenocorticotropic hormone, and others, resulting in symptoms like fatigue, weight gain, decreased libido, and growth issues in children. The pituitary gland's dysfunction can also lead to secondary adrenal insufficiency, thyroid dysfunction, and reproductive issues. Accurate diagnosis often requires a combination of clinical evaluation, hormone level testing, and imaging studies. Treatment typically involves hormone replacement therapy and addressing the underlying cause of the pituitary dysfunction. Understanding the interplay between the pituitary gland and other endocrine glands is essential for managing these disorders effectively.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of symptoms that can overlap with other endocrine disorders
  • Need for comprehensive hormone level testing
  • Potential for multiple underlying causes requiring differential diagnosis
  • Variability in clinical presentation among patients

Audit Risk Factors

  • Inadequate documentation of hormone levels
  • Failure to document the clinical rationale for testing
  • Lack of follow-up notes on treatment efficacy
  • Misclassification of symptoms related to other endocrine disorders

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed hormone level tests, patient history, and treatment plans must be documented.

Common Clinical Scenarios

Patients presenting with fatigue, weight changes, or reproductive issues requiring hormone evaluation.

Billing Considerations

Endocrinologists must ensure that all relevant hormone levels are tested and documented to support the diagnosis.

Pediatrics

Documentation Requirements

Growth charts, developmental milestones, and family history of endocrine disorders.

Common Clinical Scenarios

Children with growth delays or abnormal puberty onset needing evaluation for pituitary disorders.

Billing Considerations

Pediatricians should document growth patterns and any signs of hormonal imbalance thoroughly.

Coding Guidelines

Inclusion Criteria

Use E23 When
  • Follow the official ICD
  • CM guidelines for coding and reporting, ensuring accurate documentation of the patient's condition, including specific hormone deficiencies and any related complications
  • Include any relevant lab results and treatment plans

Exclusion Criteria

Do NOT use E23 When
No specific exclusions found.

Related CPT Codes

84443CPT Code

Thyroid-stimulating hormone (TSH) test

Clinical Scenario

Used to evaluate thyroid function in patients suspected of having pituitary disorders.

Documentation Requirements

Document the clinical rationale for testing and any relevant patient history.

Specialty Considerations

Endocrinologists should ensure comprehensive hormone panels are ordered.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of pituitary disorders, improving the accuracy of diagnoses and treatment plans. This specificity aids in better tracking of patient outcomes and resource allocation.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of pituitary disorders, improving the accuracy of diagnoses and treatment plans. This specificity aids in better tracking of patient outcomes and resource allocation.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of pituitary disorders, improving the accuracy of diagnoses and treatment plans. This specificity aids in better tracking of patient outcomes and resource allocation.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common symptoms of hypofunction of the pituitary gland?

Common symptoms include fatigue, weight gain, decreased libido, growth delays in children, and symptoms of adrenal insufficiency such as low blood pressure and weakness.