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ICD-10 Guide
ICD-10 CodesE23.3

E23.3

Billable

Hypothalamic dysfunction, not elsewhere classified

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E23.3 is a billable code used to indicate a diagnosis of hypothalamic dysfunction, not elsewhere classified.

Key Diagnostic Point:

Hypothalamic dysfunction refers to a range of disorders that arise from the dysfunction of the hypothalamus, a critical brain region that regulates various endocrine functions. This condition can lead to imbalances in hormones produced by the pituitary gland, adrenal glands, and other endocrine organs. Symptoms may include abnormal growth patterns, metabolic disturbances, and reproductive issues due to the hypothalamus's role in regulating the endocrine system. The dysfunction can manifest as either hyperfunction or hypofunction of the hypothalamus, leading to conditions such as obesity, adrenal insufficiency, or hypopituitarism. Diagnosis typically involves a combination of clinical evaluation, hormonal assays, and imaging studies to assess the hypothalamus and associated glands. Treatment may involve hormone replacement therapy, lifestyle modifications, or addressing underlying causes such as tumors or genetic disorders. Given the complexity of the endocrine system, accurate diagnosis and management of hypothalamic dysfunction require a multidisciplinary approach.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Variety of symptoms that can overlap with other endocrine disorders
  • Need for comprehensive hormonal evaluation
  • Potential involvement of multiple endocrine glands
  • Variability in clinical presentation among patients

Audit Risk Factors

  • Inadequate documentation of symptoms and clinical findings
  • Failure to document hormonal assay results
  • Lack of clear treatment plans or follow-up
  • Misclassification of the condition due to overlapping symptoms

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed hormonal assay results, imaging studies, and clinical evaluations.

Common Clinical Scenarios

Patients presenting with unexplained weight changes, menstrual irregularities, or growth abnormalities.

Billing Considerations

Endocrinologists must ensure comprehensive documentation of all endocrine evaluations and treatments.

Neurology

Documentation Requirements

Neurological assessments, imaging results, and any relevant neurological symptoms.

Common Clinical Scenarios

Patients with neurological symptoms that may suggest hypothalamic involvement, such as seizures or cognitive changes.

Billing Considerations

Neurologists should document any neurological deficits and their potential relationship to hypothalamic dysfunction.

Coding Guidelines

Inclusion Criteria

Use E23.3 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the diagnosis is supported by clinical documentation
  • Include any relevant laboratory results and imaging studies that confirm the diagnosis

Exclusion Criteria

Do NOT use E23.3 When
  • Exclude conditions that are specifically classified elsewhere

Related ICD-10 Codes

Related CPT Codes

84403CPT Code

Thyroid-stimulating hormone (TSH) test

Clinical Scenario

Used to evaluate thyroid function in patients with suspected hypothalamic dysfunction.

Documentation Requirements

Document the reason for the test and any relevant clinical findings.

Specialty Considerations

Endocrinologists should ensure that the test results are interpreted in the context of the patient's overall endocrine status.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of hypothalamic dysfunction, improving the ability to capture the complexity of endocrine disorders and their management.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of hypothalamic dysfunction, improving the ability to capture the complexity of endocrine disorders and their management.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common symptoms of hypothalamic dysfunction?

Common symptoms include weight changes, menstrual irregularities, fatigue, and growth abnormalities due to hormonal imbalances.

How is hypothalamic dysfunction diagnosed?

Diagnosis typically involves a combination of clinical evaluation, hormonal assays, and imaging studies to assess the hypothalamus and associated glands.