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ICD-10 Guide
ICD-10 CodesE25.8

E25.8

Billable

Other adrenogenital disorders

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E25.8 is a billable code used to indicate a diagnosis of other adrenogenital disorders.

Key Diagnostic Point:

Other adrenogenital disorders encompass a range of conditions characterized by abnormal hormone production from the adrenal glands, leading to various clinical manifestations. These disorders often result from adrenal hyperplasia, tumors, or other dysfunctions affecting adrenal hormone synthesis, particularly androgens. Patients may present with symptoms such as hirsutism, virilization, menstrual irregularities, and infertility in females, while males may exhibit precocious puberty or other signs of androgen excess. The underlying pathophysiology often involves disruptions in the hypothalamic-pituitary-adrenal (HPA) axis, leading to altered levels of adrenocorticotropic hormone (ACTH) and subsequent adrenal steroid production. Diagnosis typically involves hormonal assays, imaging studies, and sometimes genetic testing to identify specific enzyme deficiencies or mutations. Treatment may include hormone replacement therapy, surgical intervention for tumors, or medications to manage symptoms and restore hormonal balance. Accurate coding is essential for proper reimbursement and to reflect the complexity of these disorders in clinical practice.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of underlying causes leading to similar symptoms
  • Need for comprehensive hormonal evaluation
  • Potential overlap with other endocrine disorders
  • Variability in clinical presentation among patients

Audit Risk Factors

  • Inadequate documentation of hormonal assays
  • Failure to specify the type of adrenogenital disorder
  • Lack of supporting clinical evidence for diagnosis
  • Misclassification of symptoms related to other endocrine disorders

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed hormonal assay results, imaging studies, and clinical symptoms must be documented.

Common Clinical Scenarios

Patients presenting with symptoms of androgen excess, such as hirsutism or menstrual irregularities.

Billing Considerations

Endocrinologists should ensure that all relevant lab results are included in the documentation to support the diagnosis.

Pediatrics

Documentation Requirements

Growth patterns, developmental milestones, and any signs of precocious puberty must be documented.

Common Clinical Scenarios

Evaluation of children with signs of early sexual development or abnormal growth patterns.

Billing Considerations

Pediatricians should be aware of the implications of early diagnosis and treatment on growth and development.

Coding Guidelines

Inclusion Criteria

Use E25.8 When
  • Follow the official ICD
  • CM coding guidelines, ensuring that the diagnosis is supported by clinical documentation
  • Include any relevant laboratory results and imaging studies that confirm the diagnosis

Exclusion Criteria

Do NOT use E25.8 When
  • Exclude conditions that are specifically defined under other codes

Related ICD-10 Codes

Related CPT Codes

84144CPT Code

Testosterone, total

Clinical Scenario

Used to evaluate patients suspected of having adrenogenital disorders.

Documentation Requirements

Document the clinical rationale for testing and any relevant symptoms.

Specialty Considerations

Endocrinologists should ensure that all relevant lab results are included in the documentation to support the diagnosis.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of adrenogenital disorders, improving the ability to capture the complexity of these conditions and their management.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of adrenogenital disorders, improving the ability to capture the complexity of these conditions and their management.

Reimbursement & Billing Impact

reimbursement.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common symptoms associated with E25.8?

Common symptoms include hirsutism, menstrual irregularities, infertility in females, and precocious puberty in males. Patients may also experience fatigue and weight changes.