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ICD-10 Guide
ICD-10 CodesE27.5

E27.5

Billable

Adrenomedullary hyperfunction

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E27.5 is a billable code used to indicate a diagnosis of adrenomedullary hyperfunction.

Key Diagnostic Point:

Adrenomedullary hyperfunction refers to an overactivity of the adrenal medulla, which is the inner part of the adrenal glands responsible for producing catecholamines, including epinephrine (adrenaline) and norepinephrine. This condition can lead to symptoms such as hypertension, palpitations, anxiety, and excessive sweating. The hypersecretion of these hormones can be caused by various factors, including tumors such as pheochromocytomas, which are often benign but can cause significant hormonal imbalances. The adrenal medulla's dysfunction can also be associated with other endocrine disorders, including those affecting the pituitary and parathyroid glands, leading to a complex interplay of hormonal regulation. Diagnosis typically involves biochemical tests to measure catecholamine levels, imaging studies to identify any tumors, and a thorough clinical evaluation to rule out other causes of similar symptoms. Management may include surgical intervention for tumors, pharmacological treatment to control symptoms, and ongoing monitoring for potential complications.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between primary and secondary causes of hyperfunction.
  • Need for comprehensive documentation of symptoms and diagnostic tests.
  • Potential overlap with other endocrine disorders.
  • Variability in clinical presentation among patients.

Audit Risk Factors

  • Inadequate documentation of symptoms and diagnostic tests.
  • Failure to specify the underlying cause of hyperfunction.
  • Misclassification of related endocrine disorders.
  • Lack of follow-up documentation for ongoing management.

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed clinical history, laboratory results, imaging studies, and treatment plans.

Common Clinical Scenarios

Patients presenting with hypertension, anxiety, and palpitations; evaluation of suspected pheochromocytoma.

Billing Considerations

Ensure comprehensive documentation of all hormonal assays and imaging results to support the diagnosis.

Surgery

Documentation Requirements

Operative reports, pre-operative evaluations, and post-operative follow-up notes.

Common Clinical Scenarios

Surgical intervention for adrenal tumors; management of complications post-surgery.

Billing Considerations

Document the rationale for surgical intervention and any findings during surgery that may impact coding.

Coding Guidelines

Inclusion Criteria

Use E27.5 When
  • Follow the official ICD
  • CM coding guidelines, ensuring accurate documentation of the condition's etiology and associated symptoms
  • Include any relevant laboratory and imaging results to substantiate the diagnosis

Exclusion Criteria

Do NOT use E27.5 When
  • Exclude conditions that do not meet the criteria for adrenomedullary hyperfunction

Related ICD-10 Codes

Related CPT Codes

74160CPT Code

CT scan of abdomen with contrast

Clinical Scenario

Used to evaluate adrenal masses in patients suspected of having adrenomedullary hyperfunction.

Documentation Requirements

Document the indication for the CT scan and any findings related to adrenal pathology.

Specialty Considerations

Endocrinologists and radiologists should collaborate to ensure accurate imaging interpretation.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of endocrine disorders, including adrenomedullary hyperfunction. This specificity aids in better tracking of patient outcomes and resource utilization, but also requires coders to be more diligent in documentation and coding practices.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of endocrine disorders, including adrenomedullary hyperfunction. This specificity aids in better tracking of patient outcomes and resource utilization, but also requires coders to be more diligent in documentation and coding practices.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of endocrine disorders, including adrenomedullary hyperfunction. This specificity aids in better tracking of patient outcomes and resource utilization, but also requires coders to be more diligent in documentation and coding practices.

Resources

Clinical References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Coding & Billing References

  • •
    ICD-10-CM Official Guidelines for Coding and Reporting

Frequently Asked Questions

What are the common symptoms of adrenomedullary hyperfunction?

Common symptoms include hypertension, palpitations, anxiety, excessive sweating, and headaches. These symptoms arise from elevated levels of catecholamines.