Primary ovarian failure
ICD-10 E28.3 is a billable code used to indicate a diagnosis of primary ovarian failure.
Primary ovarian failure, also known as primary ovarian insufficiency (POI), is a condition characterized by the loss of normal ovarian function before the age of 40. This condition can lead to irregular or absent menstrual periods, infertility, and symptoms associated with estrogen deficiency, such as hot flashes, night sweats, and vaginal dryness. The etiology of primary ovarian failure can be multifactorial, including genetic factors, autoimmune disorders, and environmental influences. Hormonal imbalances are common, particularly involving estrogen and progesterone, which can lead to secondary effects on the pituitary and adrenal glands. The pituitary gland may respond to low estrogen levels by increasing the secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which can be elevated in patients with POI. Additionally, conditions such as Turner syndrome, Fragile X syndrome, and autoimmune diseases like Addison's disease can contribute to the development of primary ovarian failure. Diagnosis typically involves a combination of clinical evaluation, hormonal assays, and imaging studies to assess ovarian structure and function. Understanding the underlying causes is crucial for management and treatment, which may include hormone replacement therapy and fertility options.
Detailed hormonal profiles, menstrual history, and fertility assessments.
Evaluation of infertility in women under 40, management of menopausal symptoms in young women.
Ensure documentation reflects the complexity of hormonal imbalances and associated conditions.
Comprehensive endocrine evaluations, including thyroid and adrenal function tests.
Assessment of patients with suspected endocrine disorders contributing to ovarian failure.
Document any coexisting endocrine disorders that may complicate the clinical picture.
Used to confirm diagnosis of primary ovarian failure.
Document the reason for testing and results.
Endocrinologists should ensure comprehensive hormonal panels are included.
Common symptoms include irregular or absent menstrual periods, hot flashes, night sweats, vaginal dryness, and infertility.
Diagnosis typically involves hormonal assays showing elevated FSH and low estrogen levels, along with clinical evaluation of symptoms.
Treatment options may include hormone replacement therapy to manage symptoms and fertility treatments for those seeking to conceive.
