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ICD-10 Guide
ICD-10 CodesE31.1

E31.1

Billable

Polyglandular hyperfunction

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E31.1 is a billable code used to indicate a diagnosis of polyglandular hyperfunction.

Key Diagnostic Point:

Polyglandular hyperfunction refers to a condition characterized by the overactivity of multiple endocrine glands, leading to an excess of hormones that can disrupt normal physiological functions. This condition often manifests during puberty, a critical period of growth and development, where hormonal imbalances can significantly impact growth patterns and sexual maturation. The thymus gland, which plays a vital role in immune function and the development of T-cells, may also be affected, leading to potential immunological disorders. Patients may experience symptoms related to hyperthyroidism, hyperparathyroidism, or adrenal hyperfunction, which can include weight loss, increased appetite, anxiety, and abnormal growth rates. The interplay between these glands can complicate diagnosis and management, as symptoms may overlap with other endocrine disorders. Accurate coding and documentation are essential for effective treatment planning and monitoring of growth abnormalities associated with polyglandular hyperfunction.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Multiple gland involvement complicates diagnosis.
  • Symptoms may overlap with other endocrine disorders.
  • Requires comprehensive hormonal evaluation.
  • Management may involve multiple specialties.

Audit Risk Factors

  • Inadequate documentation of gland involvement.
  • Failure to specify hormonal levels.
  • Misclassification of symptoms.
  • Lack of interdisciplinary communication.

Specialty Focus

Medical Specialties

Endocrinology

Documentation Requirements

Detailed hormonal assay results and gland-specific symptoms.

Common Clinical Scenarios

Patients presenting with unexplained weight changes, growth abnormalities, or signs of hyperfunction.

Billing Considerations

Ensure all relevant endocrine evaluations are documented to support the diagnosis.

Pediatrics

Documentation Requirements

Growth charts and developmental milestones must be included.

Common Clinical Scenarios

Adolescents with abnormal growth patterns or delayed puberty.

Billing Considerations

Consider psychosocial factors affecting growth and development.

Coding Guidelines

Inclusion Criteria

Use E31.1 When
  • Follow official ICD
  • 10 guidelines for coding endocrine disorders, ensuring specificity in gland involvement and symptoms
  • Include any relevant laboratory results to support the diagnosis

Exclusion Criteria

Do NOT use E31.1 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

84443CPT Code

Thyroid stimulating hormone (TSH)

Clinical Scenario

Used to evaluate thyroid function in patients with suspected hyperthyroidism.

Documentation Requirements

Document the rationale for testing and any relevant clinical findings.

Specialty Considerations

Endocrinologists should ensure comprehensive thyroid evaluations are performed.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of polyglandular hyperfunction, improving the accuracy of diagnoses and treatment plans. This specificity aids in better tracking of patient outcomes and resource allocation.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of polyglandular hyperfunction, improving the accuracy of diagnoses and treatment plans. This specificity aids in better tracking of patient outcomes and resource allocation.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of polyglandular hyperfunction, improving the accuracy of diagnoses and treatment plans. This specificity aids in better tracking of patient outcomes and resource allocation.

Resources

Clinical References

  • •
    American Association of Clinical Endocrinologists

Coding & Billing References

  • •
    American Association of Clinical Endocrinologists

Frequently Asked Questions

What are the common symptoms of polyglandular hyperfunction?

Common symptoms include weight changes, increased appetite, anxiety, fatigue, and abnormal growth patterns, depending on which glands are affected.