Multiple endocrine neoplasia [MEN] type I
ICD-10 E31.21 is a billable code used to indicate a diagnosis of multiple endocrine neoplasia [men] type i.
Multiple endocrine neoplasia type I (MEN I), also known as Wermer's syndrome, is a hereditary condition characterized by the development of tumors in multiple endocrine glands. The most commonly affected glands include the parathyroid glands, pancreas, and pituitary gland. Patients with MEN I often present with hyperparathyroidism, which can lead to hypercalcemia and associated complications such as kidney stones and osteoporosis. Pancreatic endocrine tumors may cause insulinomas or gastrinomas, leading to hypoglycemia or Zollinger-Ellison syndrome, respectively. Pituitary tumors can result in hormonal imbalances, affecting growth and metabolism. The condition is associated with genetic mutations, primarily in the MEN1 gene, and typically manifests in adulthood, although some symptoms may arise during puberty. Due to the polyglandular nature of the disorder, patients may experience a range of symptoms related to hormonal dysfunction, including growth abnormalities and thymus disorders. Early diagnosis and management are crucial to prevent complications and improve quality of life.
Detailed documentation of hormonal levels, imaging studies, and tumor types.
Patients presenting with hypercalcemia, insulinomas, or pituitary adenomas.
Ensure comprehensive documentation of all endocrine glands involved.
Family history, genetic testing results, and counseling notes.
Patients with a family history of MEN I or related endocrine tumors.
Document genetic counseling and testing to support diagnosis.
Used when tumor biopsies are taken for diagnosis.
Pathology reports must be included.
Endocrinologists and pathologists must collaborate on documentation.
Common symptoms include hypercalcemia, recurrent kidney stones, hypoglycemia, and hormonal imbalances due to pituitary tumors.
