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v1.0.0
ICD-10 Guide
ICD-10 CodesE34.0

E34.0

Billable

Carcinoid syndrome

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E34.0 is a billable code used to indicate a diagnosis of carcinoid syndrome.

Key Diagnostic Point:

Carcinoid syndrome is a group of symptoms that occur in patients with carcinoid tumors, which are neuroendocrine tumors that typically arise in the gastrointestinal tract, particularly the small intestine, or the lungs. These tumors can secrete various hormones, most notably serotonin, which leads to characteristic symptoms. The syndrome is marked by flushing of the skin, diarrhea, wheezing, and abdominal pain. The flushing is often episodic and can be triggered by certain foods or stress. Diarrhea can be profuse and is often accompanied by abdominal cramping. Patients may also experience heart valve abnormalities due to the effects of serotonin on the heart, leading to carcinoid heart disease. Diagnosis is typically confirmed through imaging studies and biochemical tests, including elevated levels of 5-Hydroxyindoleacetic acid (5-HIAA) in urine. Management involves treating the underlying tumor, often with surgical resection, and symptomatic relief through medications such as somatostatin analogs. Understanding carcinoid syndrome is crucial for effective coding and billing, as it can significantly impact patient management and outcomes.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of symptoms that can overlap with other conditions
  • Need for precise documentation of hormone levels and imaging results
  • Potential for multiple related diagnoses (e.g., carcinoid heart disease)
  • Variability in tumor location and associated symptoms

Audit Risk Factors

  • Inadequate documentation of symptoms and their severity
  • Failure to document the relationship between carcinoid tumors and syndrome symptoms
  • Misclassification of symptoms as unrelated conditions
  • Inconsistent reporting of biochemical markers

Specialty Focus

Medical Specialties

Oncology

Documentation Requirements

Detailed pathology reports, imaging studies, and treatment plans.

Common Clinical Scenarios

Patients presenting with gastrointestinal symptoms and a known history of carcinoid tumors.

Billing Considerations

Ensure all tumor markers and symptoms are documented to support the diagnosis.

Endocrinology

Documentation Requirements

Hormonal assay results, patient history of flushing and diarrhea, and treatment response.

Common Clinical Scenarios

Patients with unexplained flushing and diarrhea who have elevated serotonin levels.

Billing Considerations

Document the correlation between hormonal levels and clinical symptoms for accurate coding.

Coding Guidelines

Inclusion Criteria

Use E34.0 When
  • According to official coding guidelines, E34
  • 0 should be used when the patient exhibits symptoms consistent with carcinoid syndrome
  • Documentation must include the presence of carcinoid tumors and the specific symptoms experienced by the patient

Exclusion Criteria

Do NOT use E34.0 When
  • Exclusion criteria include other causes of flushing or diarrhea that are not related to carcinoid tumors

Related ICD-10 Codes

Related CPT Codes

88305CPT Code

Pathology examination of carcinoid tumor

Clinical Scenario

Used when a biopsy of a suspected carcinoid tumor is performed.

Documentation Requirements

Pathology report must confirm the presence of carcinoid tumor.

Specialty Considerations

Oncology specialists should ensure that all tumor characteristics are documented.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of carcinoid syndrome, improving the accuracy of diagnosis and treatment tracking. The granularity of ICD-10 codes helps in better understanding the prevalence and management of carcinoid tumors and their associated syndromes.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of carcinoid syndrome, improving the accuracy of diagnosis and treatment tracking. The granularity of ICD-10 codes helps in better understanding the prevalence and management of carcinoid tumors and their associated syndromes.

Reimbursement & Billing Impact

reimbursement and to avoid claim denials.

Resources

Clinical References

  • •
    Carcinoid Cancer Foundation

Coding & Billing References

  • •
    Carcinoid Cancer Foundation

Frequently Asked Questions

What are the common symptoms of carcinoid syndrome?

Common symptoms include flushing, diarrhea, wheezing, and abdominal pain, often triggered by certain foods or stress.

How is carcinoid syndrome diagnosed?

Diagnosis is typically made through imaging studies, biopsy of the tumor, and elevated levels of 5-HIAA in urine.

What treatments are available for carcinoid syndrome?

Treatment options include surgical resection of the tumor, medications like somatostatin analogs, and management of symptoms.