Insulin-like growth factor-1 (IGF-1) resistance
ICD-10 E34.322 is a billable code used to indicate a diagnosis of insulin-like growth factor-1 (igf-1) resistance.
Insulin-like growth factor-1 (IGF-1) resistance is a condition characterized by the body's inability to respond effectively to IGF-1, a hormone that plays a crucial role in growth and development. This resistance can lead to various growth abnormalities, particularly during puberty, where normal growth patterns are disrupted. Patients may present with short stature, delayed puberty, and other endocrine dysfunctions. The condition can be associated with polyglandular dysfunction, where multiple endocrine glands are affected, leading to a complex interplay of hormonal imbalances. Thymus disorders may also be implicated, as the thymus plays a role in immune function and can influence growth factors. Diagnosing IGF-1 resistance typically involves measuring IGF-1 levels, alongside growth hormone levels, and assessing the patient's growth patterns over time. Treatment may include hormone therapy and addressing any underlying endocrine disorders.
Detailed endocrine evaluations, including hormone levels and growth assessments.
Patients presenting with short stature, delayed puberty, or unexplained growth abnormalities.
Ensure all relevant lab results and growth charts are included in documentation.
Growth charts, family history of growth disorders, and developmental milestones.
Children with growth delays or abnormal growth patterns requiring referral to endocrinology.
Documenting the child's growth history and any interventions attempted.
Used to confirm IGF-1 levels in patients suspected of having IGF-1 resistance.
Document the reason for testing and any relevant clinical findings.
Endocrinologists should ensure comprehensive lab results are included.
Common symptoms include short stature, delayed puberty, and other growth abnormalities. Patients may also exhibit signs of other endocrine dysfunctions.
