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v1.0.0
ICD-10 Guide
ICD-10 CodesE51.8

E51.8

Billable

Other manifestations of thiamine deficiency

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 E51.8 is a billable code used to indicate a diagnosis of other manifestations of thiamine deficiency.

Key Diagnostic Point:

Thiamine deficiency, also known as vitamin B1 deficiency, can lead to a variety of clinical manifestations beyond the well-known conditions of beriberi and Wernicke-Korsakoff syndrome. Patients may present with neurological symptoms such as peripheral neuropathy, muscle weakness, and cognitive impairments. Cardiovascular manifestations can include tachycardia and edema. In some cases, thiamine deficiency may also contribute to metabolic derangements, particularly in individuals with chronic alcoholism or malnutrition. The deficiency is often exacerbated by conditions that impair absorption or increase the body's demand for thiamine, such as diabetes or hyperthyroidism. Diagnosis typically involves clinical assessment and may be supported by laboratory tests measuring thiamine levels. Treatment includes dietary modifications to increase thiamine intake, such as incorporating whole grains, legumes, nuts, and fortified foods, along with thiamine supplementation as needed. Understanding the broader implications of thiamine deficiency is crucial for effective management and prevention of complications.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Variety of clinical manifestations that may not be immediately recognized as thiamine deficiency.
  • Overlap with other vitamin deficiencies, complicating diagnosis.
  • Need for comprehensive patient history to identify risk factors.
  • Potential for misdiagnosis due to similar presentations with other neurological or cardiovascular conditions.

Audit Risk Factors

  • Inadequate documentation of dietary history.
  • Failure to link symptoms to thiamine deficiency.
  • Misclassification of symptoms as unrelated conditions.
  • Lack of follow-up documentation on treatment efficacy.

Specialty Focus

Medical Specialties

Nutrition

Documentation Requirements

Detailed dietary assessments and patient history.

Common Clinical Scenarios

Patients with malnutrition, chronic alcoholism, or gastrointestinal disorders.

Billing Considerations

Emphasis on dietary intake and supplementation adherence.

Neurology

Documentation Requirements

Neurological assessments and symptom descriptions.

Common Clinical Scenarios

Patients presenting with cognitive decline or peripheral neuropathy.

Billing Considerations

Differentiating between thiamine deficiency and other neurological disorders.

Coding Guidelines

Inclusion Criteria

Use E51.8 When
  • According to ICD
  • 10 guidelines, E51
  • 8 should be used when the specific manifestation of thiamine deficiency does not fit into other defined categories
  • It is important to document the clinical context and any related symptoms to support the use of this code

Exclusion Criteria

Do NOT use E51.8 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

99213CPT Code

Established patient office visit, Level 3

Clinical Scenario

Used for follow-up visits to monitor thiamine deficiency treatment.

Documentation Requirements

Document patient history, dietary intake, and treatment response.

Specialty Considerations

Nutrition specialists should focus on dietary assessments.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of thiamine deficiency and its manifestations, improving the accuracy of diagnoses and treatment tracking. E51.8 provides a catch-all for cases that do not fit into more specific categories, enhancing the ability to capture the full spectrum of thiamine deficiency-related conditions.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of thiamine deficiency and its manifestations, improving the accuracy of diagnoses and treatment tracking. E51.8 provides a catch-all for cases that do not fit into more specific categories, enhancing the ability to capture the full spectrum of thiamine deficiency-related conditions.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of thiamine deficiency and its manifestations, improving the accuracy of diagnoses and treatment tracking. E51.8 provides a catch-all for cases that do not fit into more specific categories, enhancing the ability to capture the full spectrum of thiamine deficiency-related conditions.

Resources

Clinical References

  • •
    National Institutes of Health - Thiamine

Coding & Billing References

  • •
    National Institutes of Health - Thiamine

Frequently Asked Questions

What are the common symptoms of thiamine deficiency?

Common symptoms include fatigue, irritability, reduced reflexes, muscle weakness, and cognitive disturbances. In severe cases, it can lead to Wernicke's encephalopathy or beriberi.

How is thiamine deficiency diagnosed?

Diagnosis is typically based on clinical symptoms, dietary history, and laboratory tests measuring thiamine levels.

What dietary sources are rich in thiamine?

Good sources of thiamine include whole grains, legumes, nuts, seeds, and fortified cereals.

What is the recommended treatment for thiamine deficiency?

Treatment involves dietary modifications to increase thiamine intake and may include thiamine supplementation, especially in high-risk populations.