Disorder of fructose metabolism, unspecified
ICD-10 E74.10 is a billable code used to indicate a diagnosis of disorder of fructose metabolism, unspecified.
Disorder of fructose metabolism refers to a group of inherited metabolic disorders that affect the body's ability to metabolize fructose, a sugar found in many fruits and sweeteners. The most common condition in this category is hereditary fructose intolerance (HFI), which results from a deficiency of the enzyme aldolase B. This enzyme is crucial for the breakdown of fructose in the liver. When fructose is ingested, individuals with this disorder may experience symptoms such as abdominal pain, vomiting, hypoglycemia, and jaundice due to the accumulation of toxic metabolites. Diagnosis typically involves clinical evaluation, dietary history, and biochemical tests to assess enzyme activity. Management primarily focuses on dietary restriction of fructose and sucrose to prevent symptoms and complications. The unspecified nature of this code indicates that the specific type of fructose metabolism disorder has not been determined, which may complicate treatment and management strategies.
Detailed growth and developmental history, dietary intake records, and symptomatology.
Infants presenting with failure to thrive, vomiting after fructose ingestion, or unexplained hypoglycemia.
Consideration of family history of metabolic disorders and genetic counseling.
Genetic testing results, family pedigree, and metabolic screening outcomes.
Patients with a family history of metabolic disorders or those presenting with unexplained metabolic crises.
Documentation of genetic counseling and potential need for enzyme replacement therapy.
Used to assess fructose metabolism in patients suspected of having a disorder.
Document the reason for the test, patient history, and results.
Pediatric specialists may require additional documentation regarding dietary intake.
Common symptoms include abdominal pain, vomiting, hypoglycemia, jaundice, and failure to thrive in infants. Symptoms can vary based on the severity of the enzyme deficiency.
