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ICD-10 Guide
ICD-10 CodesF11.25

F11.25

Billable

Opioid dependence with opioid-induced psychotic disorder

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 F11.25 is a billable code used to indicate a diagnosis of opioid dependence with opioid-induced psychotic disorder.

Key Diagnostic Point:

Opioid dependence with opioid-induced psychotic disorder is characterized by a pattern of opioid use leading to clinically significant impairment or distress, accompanied by the presence of psychotic symptoms directly attributable to opioid use. Patients may experience hallucinations, delusions, or disorganized thinking as a result of their opioid consumption. This condition often arises in individuals who misuse prescription opioids or illicit opioids, leading to a cycle of dependence and exacerbation of mental health issues. The diagnosis requires careful assessment of the patient's history, including the duration and quantity of opioid use, the onset of psychotic symptoms in relation to opioid use, and the exclusion of other potential causes of psychosis. Treatment typically involves a combination of pharmacotherapy, such as methadone or buprenorphine, and psychosocial interventions, including cognitive-behavioral therapy and support groups, to address both the substance use disorder and the associated psychotic symptoms.

Code Complexity Analysis

Complexity Rating: High

High Complexity

Complexity Factors

  • Differentiating between primary psychotic disorders and substance-induced psychosis.
  • Need for comprehensive documentation of substance use history.
  • Potential for co-occurring mental health disorders complicating diagnosis.
  • Variability in symptom presentation among patients.

Audit Risk Factors

  • Inadequate documentation of psychotic symptoms.
  • Failure to establish a clear timeline of opioid use and symptom onset.
  • Misclassification of opioid-induced psychosis as a primary psychotic disorder.
  • Lack of evidence for treatment plans addressing both substance use and psychosis.

Specialty Focus

Medical Specialties

Psychiatry

Documentation Requirements

Detailed psychiatric evaluation, including mental status examination and history of substance use.

Common Clinical Scenarios

Patients presenting with acute psychosis following opioid use or those with chronic opioid dependence exhibiting psychotic features.

Billing Considerations

Consideration of differential diagnoses and the impact of co-occurring disorders on treatment.

Addiction Medicine

Documentation Requirements

Comprehensive assessment of substance use history, including types of opioids used and duration of use.

Common Clinical Scenarios

Patients in withdrawal experiencing psychotic symptoms or those in treatment programs with a history of opioid dependence.

Billing Considerations

Integration of psychosocial support and monitoring of treatment adherence.

Coding Guidelines

Inclusion Criteria

Use F11.25 When
  • According to ICD
  • 10 guidelines, F11
  • 25 should be used when there is clear evidence of opioid dependence accompanied by psychotic symptoms directly related to opioid use
  • Documentation must support the diagnosis, including the timeline of substance use and symptomatology

Exclusion Criteria

Do NOT use F11.25 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

99214CPT Code

Established patient office visit, level 4

Clinical Scenario

Used for follow-up visits for patients with opioid dependence and psychotic symptoms.

Documentation Requirements

Document the patient's history, mental status, and treatment plan.

Specialty Considerations

Psychiatrists should ensure comprehensive mental health assessments are included.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of opioid-related disorders, improving the ability to capture the complexity of conditions like F11.25. This specificity aids in better treatment planning and resource allocation.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of opioid-related disorders, improving the ability to capture the complexity of conditions like F11.25. This specificity aids in better treatment planning and resource allocation.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of opioid-related disorders, improving the ability to capture the complexity of conditions like F11.25. This specificity aids in better treatment planning and resource allocation.

Resources

Clinical References

  • •
    Substance Abuse and Mental Health Services Administration (SAMHSA)

Coding & Billing References

  • •
    Substance Abuse and Mental Health Services Administration (SAMHSA)

Frequently Asked Questions

What is the difference between opioid dependence and opioid-induced psychotic disorder?

Opioid dependence refers to the compulsive use of opioids leading to significant impairment, while opioid-induced psychotic disorder specifically involves the presence of psychotic symptoms that arise as a direct result of opioid use.