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ICD-10 Guide
ICD-10 CodesF12.221

F12.221

Billable

Cannabis dependence with intoxication delirium

BILLABLE STATUSYes
IMPLEMENTATION DATEOctober 1, 2015
LAST UPDATED09/05/2025

Code Description

ICD-10 F12.221 is a billable code used to indicate a diagnosis of cannabis dependence with intoxication delirium.

Key Diagnostic Point:

Cannabis dependence with intoxication delirium is characterized by a pattern of cannabis use leading to clinically significant impairment or distress, accompanied by acute confusion, disorientation, and altered consciousness due to recent cannabis use. Individuals may exhibit symptoms such as hallucinations, agitation, and cognitive disturbances, which can significantly impair their ability to function in daily life. The diagnosis requires evidence of cannabis dependence, which may include tolerance, withdrawal symptoms, and a persistent desire to use cannabis despite negative consequences. The delirium aspect indicates that the individual is experiencing an acute episode of confusion and cognitive dysfunction, often requiring immediate medical attention. Treatment typically involves supportive care, monitoring, and possibly pharmacological interventions to manage symptoms. Long-term management may include behavioral therapies and substance use disorder treatment programs aimed at reducing dependence and preventing relapse.

Code Complexity Analysis

Complexity Rating: Medium

Medium Complexity

Complexity Factors

  • Differentiating between intoxication delirium and other psychiatric conditions.
  • Need for comprehensive documentation of substance use history.
  • Potential overlap with other substance use disorders.
  • Variability in symptoms and severity among patients.

Audit Risk Factors

  • Inadequate documentation of the severity of delirium.
  • Failure to document the history of cannabis use.
  • Misclassification of symptoms as unrelated psychiatric disorders.
  • Lack of evidence for the impact of cannabis use on daily functioning.

Specialty Focus

Medical Specialties

Psychiatry

Documentation Requirements

Detailed patient history, including substance use patterns and mental health history.

Common Clinical Scenarios

Patients presenting with acute confusion and a known history of cannabis use.

Billing Considerations

Consideration of co-occurring mental health disorders and their impact on treatment.

Addiction Medicine

Documentation Requirements

Comprehensive assessment of substance use, including frequency, quantity, and impact on life.

Common Clinical Scenarios

Patients in withdrawal or experiencing acute intoxication symptoms.

Billing Considerations

Integration of behavioral health interventions with pharmacotherapy.

Coding Guidelines

Inclusion Criteria

Use F12.221 When
  • Follow the ICD
  • CM guidelines for coding substance use disorders, ensuring accurate documentation of the dependence and delirium
  • Include details on the duration and severity of symptoms

Exclusion Criteria

Do NOT use F12.221 When
No specific exclusions found.

Related ICD-10 Codes

Related CPT Codes

99214CPT Code

Established patient office visit, level 4

Clinical Scenario

Used for follow-up visits after initial assessment of cannabis dependence.

Documentation Requirements

Document history, examination findings, and treatment plan.

Specialty Considerations

Psychiatric evaluations may require additional documentation.

ICD-10 Impact

Diagnostic & Documentation Impact

Enhanced Specificity

ICD-10 Improvements

The transition to ICD-10 has allowed for more specific coding of cannabis-related disorders, improving the accuracy of diagnoses and treatment planning.

ICD-9 vs ICD-10

The transition to ICD-10 has allowed for more specific coding of cannabis-related disorders, improving the accuracy of diagnoses and treatment planning.

Reimbursement & Billing Impact

The transition to ICD-10 has allowed for more specific coding of cannabis-related disorders, improving the accuracy of diagnoses and treatment planning.

Resources

Clinical References

  • •
    Substance Abuse and Mental Health Services Administration (SAMHSA)

Coding & Billing References

  • •
    Substance Abuse and Mental Health Services Administration (SAMHSA)

Frequently Asked Questions

What are the key symptoms of cannabis dependence with intoxication delirium?

Key symptoms include confusion, disorientation, hallucinations, and cognitive impairment, often occurring after heavy cannabis use.